2. Gene
  3. PARP15 - poly(ADP-ribose) polymerase family member 15 Gene

PARP15 - poly(ADP-ribose) polymerase family member 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品

中文名称：聚 (ADP-核糖) 聚合酶家族成员 15

种属: Homo sapiens

同用名: BAL3; ARTD7; pART7

基因 ID: 165631 | 基因类型: protein coding

关于 PARP15

Cytogenetic location: 3q21.1 Genomic coordinates (GRCh38): 3:122,577,650-122,639,047 (from NCBI)

This gene has 6 transcripts (splice variants), 449 orthologues and 8 paralogues. Biased expression in spleen (RPKM 9.7), lymph node (RPKM 8.3) and 8 other tissues.

功能概要

PARP15 是一种具有聚 (ADP-核糖) 聚合酶活性的含有宏结构域的转录抑制因子 (Aguiar 等人，2005 [PubMed 16061477]) 。[OMIM 提供，2008 年 5 月]

PARP15 is a macrodomain-containing transcriptional repressor with poly(ADP-ribose) polymerase activity (Aguiar et al., 2005 [PubMed 16061477]).[supplied by OMIM, May 2008]

PARP15 基因产物(17)

mRNA Protein Name
XM_017005792.3 XP_016861281.1 protein mono-ADP-ribosyltransferase PARP15 isoform X9
XM_047447582.1 XP_047303538.1 protein mono-ADP-ribosyltransferase PARP15 isoform X8
XM_005247159.5 XP_005247216.1 protein mono-ADP-ribosyltransferase PARP15 isoform X3
XM_011512476.4 XP_011510778.1 protein mono-ADP-ribosyltransferase PARP15 isoform X2
NM_001308321.2 NP_001295250.1 protein mono-ADP-ribosyltransferase PARP15 isoform 4 precursor
XM_047447583.1 XP_047303539.1 protein mono-ADP-ribosyltransferase PARP15 isoform X9
XM_011512479.4 XP_011510781.1 protein mono-ADP-ribosyltransferase PARP15 isoform X9
XM_047447580.1 XP_047303536.1 protein mono-ADP-ribosyltransferase PARP15 isoform X5
XM_011512475.4 XP_011510777.1 protein mono-ADP-ribosyltransferase PARP15 isoform X1
XM_005247160.5 XP_005247217.1 protein mono-ADP-ribosyltransferase PARP15 isoform X4
NM_001113523.3 NP_001106995.1 protein mono-ADP-ribosyltransferase PARP15 isoform 1
XM_047447584.1 XP_047303540.1 protein mono-ADP-ribosyltransferase PARP15 isoform X10
XM_011512480.4 XP_011510782.1 protein mono-ADP-ribosyltransferase PARP15 isoform X11
XM_017005791.3 XP_016861280.1 protein mono-ADP-ribosyltransferase PARP15 isoform X7
NM_001308320.2 NP_001295249.1 protein mono-ADP-ribosyltransferase PARP15 isoform 3
NM_152615.3 NP_689828.1 protein mono-ADP-ribosyltransferase PARP15 isoform 2 precursor
XM_011512477.4 XP_011510779.1 protein mono-ADP-ribosyltransferase PARP15 isoform X6

PARP15 蛋白结构

Macro

Macro: Macro domain (107 - 221)

Macro

Macro: Macro domain (322 - 416)

PARP

PARP: Poly(ADP-ribose) polymerase catalytic domain (496 - 676)

  • 0
  • 200
  • 400
  • 600
  • 678 a.a.
蛋白主名 其他名称

protein mono-ADP-ribosyltransferase PARP15

ADP-ribosyltransferase diphtheria toxin-like 7

B-aggressive lymphoma 3

B-aggressive lymphoma protein 3

PARP-15

poly [ADP-ribose] polymerase 15

关联疾病

疾病名称 别名
Yaws

Frambesia

Frambesia Tropica

Bouba

Frambosie

Polypapilloma Tropicum

Thymosis

Endemic Treponematoses

Treponema Pertenue Infection

Pian

Framboesia

Framboesia Tropica

Castellani

Infection By Treponema Pertenue

Parangi

Framboesioma

Chancre Of Yaws

Primary Framboesia

Initial Lesions Of Yaws

Mother Yaw

Initial Framboesia
Bejel

Njovera

Dichuchwa

Nonvenereal Endemic Syphilis

Endemic Syphilis

Frenga

Nonvenereal Syphilis

Treponemal Infections

Non-Venereal Endemic Syphilis

Siti

Skerljevo

Belesh
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-150207 RBN-3143 Inhibitor 99.24% 否
HY-143398 PARP10/15-IN-1 Inhibitor 95.00% 否
HY-148566 OUL232 Inhibitor 99.82% 否
HY-146502 PARP10/15-IN-3 Inhibitor 99.98% 否
HY-121719 TIQ-A Inhibitor 99.65% 否
HY-143338 ART-IN-1 Inhibitor 98.91% 否
HY-146501 PARP10/15-IN-2 Inhibitor 99.00% 否
HY-148754 PARP10-IN-3 Inhibitor 98.89% 否
HY-W294889 OUL245 Inhibitor / 否
HY-148709 ARTD10/PARP10-IN-1 Inhibitor / 否
HY-155993 YCH1899 Inhibitor / 否
HY-148753 PARP10-IN-2 Inhibitor 98.02% 否
HY-148710 ARTD10/PARP10-IN-2 Inhibitor / 否
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