2. Gene
  3. FABP7 - fatty acid binding protein 7 Gene

FABP7 - fatty acid binding protein 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脂肪酸结合蛋白 7

种属: Homo sapiens

同用名: MRG; BLBP; FABPB; B-FABP

基因 ID: 2173 | 基因类型: protein coding

关于 FABP7

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:122,749,201-122,784,074 (from NCBI)

This gene has 2 transcripts (splice variants), 283 orthologues and 15 paralogues. Biased expression in brain (RPKM 8.9) and skin (RPKM 0.4).

功能概要

该基因编码一种小的、高度保守的细胞质蛋白，可结合长链脂肪酸和其他疏水配体。编码的蛋白质对于在发育中的大脑中建立放射状神经胶质纤维很重要。选择性剪接和启动子的使用导致编码不同异构体的多个转录变体。该基因的假基因存在于多条染色体上。[RefSeq 提供，2016 年 1 月]

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

FABP7 基因产物(4)

mRNA Protein Name
NM_001319039.2 NP_001305968.1 fatty acid-binding protein, brain isoform 2
NM_001319041.2 NP_001305970.1 fatty acid-binding protein, brain isoform 3
NM_001319042.2 NP_001305971.1 fatty acid-binding protein, brain isoform 4
NM_001446.5 NP_001437.1 fatty acid-binding protein, brain isoform 1

FABP7 蛋白结构

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (8 - 131)

  • 0
  • 100
  • 132 a.a.
蛋白主名 其他名称

fatty acid-binding protein, brain

brain lipid-binding protein

重组 FABP7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7666 FABP7 Protein, Human (His) O15540 (V2-A132) ≥95%
HY-P70200 Recombinant Human Fatty acid-binding protein/FABP7, His O15540 ≥95%

关联疾病

疾病名称 别名
Adult Central Nervous System Primitive Neuroectodermal Neoplasm

Adult Cns Pnet

Adult Central Nervous System Primitive Neuroectodermal Tumor
High Grade Glioma

Malignant Glioma

Glial Cell Tumor

Glioma, Malignant

Malignant Neuroglial Tumor

Neuroglial Tumor

Glioma

Malignant Gliomas
Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma

RCC

Nonpapillary Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

Hypernephroma

Adenocarcinoma Of Kidney

Renal Carcinoma, Chromophobe, Somatic

Clear Cell Carcinoma Of Kidney

Clear-Cell Metastatic Renal Cell Carcinoma

Clear Cell Renal Carcinoma

Renal Cell Carcinoma, Somatic

Conventional Renal Cell Carcinoma

Conventional Renal Cell Carcinoma

Renal Clear Cell Carcinoma

Ccrcc

Hereditary Clear Cell Renal Cell Carcinoma

Carcinoma, Renal Cell

Renal Cell Carcinoma, Clear Cell, Somatic

Renal Cell Carcinoma, Clear Cell

Clear Cell Kidney Carcinoma

Clear Cell Rcc

Cystic-Multilocular Variant

Clear Cell Renal Cell Adenocarcinoma

Hereditary Clear Cell Renal Cell Adenocarcinoma

Common Renal Cell Carcinoma

Crcc

Renal Cell Carcinoma Non-Papillary

Carcinoma Renal Cell

Renal Cell Cancer

Carcinoma, Renal Cell, Nonpapillary
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
Hirschsprung Disease 1

Hirschsprung Disease

Aganglionic Megacolon

Hscr

Hirschsprung'S Disease

Congenital Megacolon

Congenital Intestinal Aganglionosis

Colonic Aganglionosis

Hirschsprung Disease, Susceptibility To, 1

Hirschsprung Disease, Protection Against

HSCR1

Mgc

Pelvirectal Achalasia

Total Intestinal Aganglionosis

Megacolon, Aganglionic

Macrocolon

Hscr 1

Hirschsprung Disease Type 1

Hirschsprung Disease, Type 1

Congenital Dilatation Of Colon

Aganglionosis

Congenital Aganglionic Megacolon

Aganglionosis Of Colon

Bowel Aganglionosis

Colon Aganglionosis

Hirschsprung Megacolon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145990 FABPs ligand 6 Inhibitor 98.57% 否
HY-RS04663 FABP7 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FABP7 VGNC VGNC:28699
Canis familiaris FABP7 VGNC VGNC:40563
Felis catus FABP7 VGNC VGNC:62037
Macaca mulatta FABP7 VGNC VGNC:104376
Mus musculus FABP7 MGD MGI:101916
Rattus norvegicus FABP7 RGD RGD:69312
Others FABP7 NCBI
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