2. Gene
  3. Oxtr - oxytocin receptor Gene

Oxtr - oxytocin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：催产素受体

种属: Rattus norvegicus

同用名: OTR; OT-R; OTR1

基因 ID: 25342 | 基因类型: protein coding

关于 Oxtr

Primary_assembly 4: 145,599,561-145,614,674 reverse strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 265 orthologues, 16 paralogues and is associated with 25 phenotypes. Biased expression in Adrenal (RPKM 17.2), Uterus (RPKM 11.7) and 7 other tissues.

功能概要

该基因编码的蛋白可启动催产素受体活性和肽激素结合活性。涉及多个过程，包括ERK1和ERK2级联；突触传递的正向调节；和分泌调节。位于adherens路口；顶端质膜；和微绒毛。用于研究胃溃疡。高血压的生物标志物。与人类 OXTR（催产素受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Oxytocin Receptor activity and peptide hormone binding activity. Involved in several processes, including ERK1 and ERK2 cascade; positive regulation of synaptic transmission; and regulation of secretion. Located in adherens junction; apical plasma membrane; and microvillus. Used to study gastric ulcer. Biomarker of hypertension. Orthologous to human OXTR (Oxytocin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Oxtr 基因产物(1)

mRNA Protein Name
NM_012871.4 NP_037003.2 oxytocin receptor

Oxtr 蛋白结构

7tmA_OT_R

7tmA_OT_R: cd15387 (39 - 338)

7tmA_OT_R

7tmA_OT_R: cd15387 (40 - 66)

7tmA_OT_R

7tmA_OT_R: cd15387 (73 - 100)

7tmA_OT_R

7tmA_OT_R: cd15387 (111 - 141)

7tmA_OT_R

7tmA_OT_R: cd15387 (151 - 172)

7tmA_OT_R

7tmA_OT_R: cd15387 (196 - 225)

7tmA_OT_R

7tmA_OT_R: cd15387 (266 - 296)

7tmA_OT_R

7tmA_OT_R: cd15387 (306 - 331)

  • 0
  • 100
  • 200
  • 300
  • 388 a.a.
蛋白主名 其他名称

oxytocin receptor

oxcytocin receptor

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108678 TC OT 39 / 否
HY-P4990 Pro8-Oxytocin Activator / 否
HY-P4990A Pro8-Oxytocin TFA Activator / 否
HY-P5017 (Val3,Pro8)-Oxytocin Agonist / 否
HY-RS09894 OXTR Human Pre-designed siRNA Set A / 否
HY-RS09895 Oxtr Mouse Pre-designed siRNA Set A / 否
HY-RS09896 Oxtr Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Oxtr NCBI NCBI:5021
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