2. Gene
  3. IGHG1 - immunoglobulin heavy constant gamma 1 (G1m marker) Gene

IGHG1 - immunoglobulin heavy constant gamma 1 (G1m marker) Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：免疫球蛋白重常数伽玛 1 (G1m 标记)

种属: Homo sapiens

基因 ID: 3500 | 基因类型: other

关于 IGHG1

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,741,473-105,743,070 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 119 orthologues, 82 paralogues and is associated with 2 phenotypes.

功能概要

预测启用抗原结合活性和免疫球蛋白受体结合活性。预计参与多个过程，包括激活免疫反应；对其他生物体的防御反应；和吞噬作用。预计在几个过程的上游或内部起作用，包括免疫球蛋白介导的免疫反应；超敏反应的正向调节；和吞噬作用的正调节。位于细胞外空间。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to act upstream of or within several processes, including immunoglobulin mediated immune response; positive regulation of hypersensitivity; and positive regulation of phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

IGHG1 蛋白结构

C1-set

C1-set: Immunoglobulin C1-set domain (15 - 92)

C1-set

C1-set: Immunoglobulin C1-set domain (130 - 216)

C1-set

C1-set: Immunoglobulin C1-set domain (236 - 318)

  • 0
  • 100
  • 200
  • 300
  • 330 a.a.

重组 IGHG1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72379 IgG1 Protein, Human (Biotinylated, HEK293, Avi) P01857 (D104-K330, D239E, L241M) ≥95%
HY-P73143 IgG1 Protein, Human (C103S, HEK293) P01857 (E99-K330, C103S) ≥95%
HY-P73902 IgG1 Protein, Human (CHO, C103S) P01857 (E99-K330, C103S) ≥95%
HY-P73903 IgG1 Protein, Human (CHO) P01857-1 (E99-K330, C103S) ≥95%
HY-P77526 IgG1 Protein, Human (Biotinylated, C103S, HEK293) P01857-1 (E99-K330, C103S) ≥95%

关联疾病

疾病名称 别名
Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell
Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration
Plasma Cell Leukemia

Plasma Cell Leukaemia

Leukemia, Plasma Cell

Plasmacytic Leukaemia

Plasmacytic Leukemia

Pcl

Plasma Cell Leukaemia, Nos

Leukemic Plasma Cell

Plasma Cell Leukaemia Without Mention Of Remission
Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99830 Conbercept / Phase 4
HY-P99844 Davoceticept / Phase 1

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IGHG1 RGD RGD:1359539
Mus musculus IGHG1 NCBI
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