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  2. TAOK3 - TAO kinase 3 Gene

TAOK3 - TAO kinase 3 Gene

中文名称:TAO 激酶 3

种属: Homo sapiens

同用名: DPK; JIK; hKFC-A; MAP3K18

基因 ID: 51347 | 基因类型: protein coding

关于 TAOK3

Cytogenetic location: 12q24.23 Genomic coordinates (GRCh38): 12:118,149,801-118,372,907 (from NCBI)

This gene has 19 transcripts (splice variants), 299 orthologues and 35 paralogues. Ubiquitous expression in brain (RPKM 12.0), prostate (RPKM 9.7) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种丝氨酸/苏氨酸蛋白激酶,可激活 p38/MAPK14 应激激活的 MAPK 级联,但抑制 MAPK8/JNK 级联的基础活性。编码的蛋白质是 STE20 样激酶的 GCK 亚家族的成员。[RefSeq 提供,2016 年 10 月]

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]

TAOK3 基因产物(12)

mRNA Protein Name
NM_001346487.2 NP_001333416.1 serine/threonine-protein kinase TAO3 isoform a
NM_001346488.2 NP_001333417.1 serine/threonine-protein kinase TAO3 isoform b
NM_001346489.2 NP_001333418.1 serine/threonine-protein kinase TAO3 isoform b
NM_001346490.2 NP_001333419.1 serine/threonine-protein kinase TAO3 isoform c
NM_001346491.2 NP_001333420.1 serine/threonine-protein kinase TAO3 isoform d
NM_001346492.2 NP_001333421.1 serine/threonine-protein kinase TAO3 isoform d
NM_001346493.2 NP_001333422.1 serine/threonine-protein kinase TAO3 isoform e
NM_001346494.2 NP_001333423.1 serine/threonine-protein kinase TAO3 isoform f
NM_001346495.2 NP_001333424.1 serine/threonine-protein kinase TAO3 isoform f
NM_001346496.2 NP_001333425.1 serine/threonine-protein kinase TAO3 isoform g
NM_001346497.2 NP_001333426.1 serine/threonine-protein kinase TAO3 isoform g
NM_016281.4 NP_057365.3 serine/threonine-protein kinase TAO3 isoform b

TAOK3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (28 - 277)

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  • 898 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase TAO3

CTCL-associated antigen HD-CL-09

重组 TAOK3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77222 TAOK3 Protein, Human (sf9, His-GST) Q9H2K8 (M1-D411) ≥95%

直系同源

种属 基因名 来源 基因 ID
Bos taurus TAOK3 VGNC VGNC:35597
Canis familiaris TAOK3 VGNC VGNC:47104
Macaca mulatta TAOK3 VGNC VGNC:81593
Felis catus TAOK3 VGNC VGNC:80496
Mus musculus TAOK3 MGD MGI:3041177
Rattus norvegicus TAOK3 RGD RGD:1562861
Others TAOK3 NCBI