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  2. IL17D - interleukin 17D Gene

IL17D - interleukin 17D Gene

中文名称:白细胞介素 17D

种属: Homo sapiens

同用名: IL-17D

基因 ID: 53342 | 基因类型: protein coding

关于 IL17D

Cytogenetic location: 13q12.11 Genomic coordinates (GRCh38): 13:20,701,513-20,723,098 (from NCBI)

This gene has 4 transcripts (splice variants), 163 orthologues and 5 paralogues. Biased expression in brain (RPKM 13.7), ovary (RPKM 2.3) and 11 other tissues.

功能概要

该基因编码的蛋白质是一种细胞因子,与 IL17 具有序列相似性。用这种细胞因子处理内皮细胞已显示可刺激其他细胞因子的产生,包括 IL6、IL8 和 CSF2/GM-CSF。发现由该细胞因子诱导的 IL8 表达增加是 NF-kappa B 依赖性的。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]

IL17D 基因产物(7)

mRNA Protein Name
NM_001385221.1 NP_001372150.1 interleukin-17D isoform a precursor
NM_001385222.1 NP_001372151.1 interleukin-17D isoform b precursor
NM_001385223.1 NP_001372152.1 interleukin-17D isoform c precursor
NM_001385224.1 NP_001372153.1 interleukin-17D isoform c precursor
NM_001385225.1 NP_001372154.1 interleukin-17D isoform d
NM_001386973.1 NP_001373902.1 interleukin-17D isoform e
NM_138284.2 NP_612141.1 interleukin-17D isoform c precursor

IL17D 蛋白结构

IL17

IL17: Interleukin-17 (89 - 171)

  • 0
  • 100
  • 202 a.a.
蛋白主名 其他名称

interleukin-17D

重组 IL17D 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70587 IL-17D Protein, Human Q8TAD2 (A18-P202) ≥95%
HY-P700106AF Animal-Free IL-17D Protein, Human (His) Q8TAD2 (A18-P202) ≥95%

关联疾病

疾病名称 别名
Hidradenitis Suppurativa

Acne Inversa

Suppurative Hidradenitis

Acne Inversa, Familial

Apocrinitis

Hidradenitides, Suppurative

Hidradenitis, Suppurative

Suppurative Hidradenitides

Inverse Acne

Psoriasis
Hidradenitis

Hydradenitis

Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders

Autoimmune Disease

Autoimmune Diseases

Autoimmune Hypersensitivity Disease

Hypersensitivity Reaction Type Ii Disease

Type Ii Hypersensitivity Reaction Disease

Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo

Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IL17D RGD RGD:1595926
Mus musculus IL17D MGD MGI:2446510
Bos taurus IL17D VGNC VGNC:30120
Others IL17D NCBI