Crhr1 - corticotropin releasing hormone receptor 1 Gene

中文名称：促肾上腺皮质激素释放激素受体 1

种属: Rattus norvegicus

同用名: CRF1; CRF-R; CRFR1; CRH-R; CRF-R1; CRFR-1; CRH-R1; CRF-R-1; CRH-R 1; CRH-R-1

关于 Crhr1

功能概要

该基因编码 G 蛋白偶联受体家族的一个成员。编码的蛋白质是促肾上腺皮质激素释放因子 (CRH) 和尿皮质素 (UCN) 的受体。这种蛋白质与 CRH 和 UCN 的相互作用触发 G 蛋白偶联信号。这种蛋白质在介导 CRH 引起的抑郁和焦虑效应中起着关键作用。已发现该基因的可变剪接转录物变体。 [RefSeq 提供，2014 年 9 月]

This gene encodes a member of the G-protein coupled receptor family. The encoded protein is a receptor for corticotropin-releasing factor (CRH) and urocortin (UCN). The interaction of this protein with CRH and UCN triggers G-protein coupled signaling. This protein plays a pivotal role in mediating the CRH-elicited effects in depression and anxiety. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]