Crhr2 - corticotropin releasing hormone receptor 2 Gene

中文名称：促肾上腺皮质激素释放激素受体 2

种属: Rattus norvegicus

同用名: Crf2r; CRF-R 2; CRH-R 2

关于 Crhr2

功能概要

该基因编码的蛋白可启动促肾上腺皮质激素释放激素受体活性和肽激素结合活性。涉及多个过程，包括分泌的负调节；基因表达的调节；和细胞内信号转导的调节。位于多个细胞成分中，包括轴突；胞体纤维；和周核体。用于研究结肠炎；缺血;和肌肉萎缩。结肠炎的生物标志物；功能性结肠疾病；肠易激综合症;和精神抑郁症。该基因的人类直系同源物与哮喘有关。与人类 CRHR2（促肾上腺皮质激素释放激素受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables corticotropin-releasing hormone receptor activity and peptide hormone binding activity. Involved in several processes, including negative regulation of secretion; regulation of gene expression; and regulation of intracellular signal transduction. Located in several cellular components, including axon; cell body fiber; and perikaryon. Used to study colitis; ischemia; and muscular atrophy. Biomarker of colitis; functional colonic disease; irritable bowel syndrome; and mental depression. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2). [provided by Alliance of Genome Resources, Apr 2022]