2. Gene
  3. RGS5 - regulator of G protein signaling 5 Gene

RGS5 - regulator of G protein signaling 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白信号调节器 5

种属: Homo sapiens

同用名: MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129

基因 ID: 8490 | 基因类型: protein coding

关于 RGS5

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:163,142,299-163,321,735 (from NCBI)

This gene has 12 transcripts (splice variants), 211 orthologues, 23 paralogues and is associated with 1 phenotype. Broad expression in adrenal (RPKM 143.5), thyroid (RPKM 96.0) and 20 other tissues.

功能概要

该基因座代表 1 号染色体上邻近的 LOC127814295 (未表征的 LOC127814295) 和 RGS5 (G 蛋白信号转导 5 的调节因子) 基因之间自然发生的通读转录。通读转录物的一些变体编码具有独特 N 末端的新型蛋白质。[RefSeq 提供，2022 年 11 月]

This locus represents naturally occurring readthrough transcription between the neighboring LOC127814295 (uncharacterized LOC127814295) and RGS5 (regulator of G-protein signaling 5) genes on chromosome 1. Some variants of the readthrough transcript encode novel proteins with unique N-termini. [provided by RefSeq, Nov 2022]

RGS5 基因产物(12)

mRNA Protein Name
NM_001195303.3 NP_001182232.1 regulator of G-protein signaling 5 isoform 2
NM_001254748.2 NP_001241677.1 regulator of G-protein signaling 5 isoform 2
NM_001254749.2 NP_001241678.1 regulator of G-protein signaling 5 isoform 3
NM_001414472.1 NP_001401401.1 regulator of G-protein signaling 5 isoform 5
NM_001414473.1 NP_001401402.1 regulator of G-protein signaling 5 isoform 5
NM_001414474.1 NP_001401403.1 regulator of G-protein signaling 5 isoform 5
NM_001414475.1 NP_001401404.1 regulator of G-protein signaling 5 isoform 5
NM_001414476.1 NP_001401405.1 regulator of G-protein signaling 5 isoform 4
NM_001414477.1 NP_001401406.1 regulator of G-protein signaling 5 isoform 2
NM_001414478.1 NP_001401407.1 regulator of G-protein signaling 5 isoform 2
NM_001414479.1 NP_001401408.1 regulator of G-protein signaling 5 isoform 2
NM_003617.4 NP_003608.1 regulator of G-protein signaling 5 isoform 1

RGS5 蛋白结构

RGS

RGS: Regulator of G protein signaling domain (64 - 179)

  • 0
  • 100
  • 181 a.a.
蛋白主名 其他名称

regulator of G-protein signaling 5

regulator of G-protein signalling 5

重组 RGS5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74596 RGS5 Protein, Human (His) O15539 (M1-K181) ≥95%
HY-P74596A RGS5 Protein, Human NP_003608 (M1-K181) /

关联疾病

疾病名称 别名
Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11923 RGS5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RGS5 MGD MGI:1098434
Canis familiaris RGS5 VGNC VGNC:53128
Rattus norvegicus RGS5 RGD RGD:3568
Macaca mulatta RGS5 VGNC VGNC:100056
Bos taurus RGS5 VGNC VGNC:55670
Others RGS5 NCBI
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