1. Gene
  2. GMFG - glia maturation factor gamma Gene

GMFG - glia maturation factor gamma Gene

中文名称:胶质细胞成熟因子γ

种属: Homo sapiens

同用名: GMF-GAMMA

基因 ID: 9535 | 基因类型: protein coding

关于 GMFG

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,328,359-39,336,043 (from NCBI)

This gene has 12 transcripts (splice variants), 178 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 133.3), spleen (RPKM 93.4) and 15 other tissues.

功能概要

预测启用 Arp2/3 复杂绑定活动。预计参与肌动蛋白丝脱支和 Arp2/3 复合物介导的肌动蛋白成核的负调节。预测位于细胞外区域;富含 ficolin-1 的颗粒管腔;和分泌颗粒腔。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in extracellular region; ficolin-1-rich granule lumen; and secretory granule lumen. [provided by Alliance of Genome Resources, Apr 2022]

GMFG 基因产物(3)

mRNA Protein Name
NM_001301008.2 NP_001287937.1 glia maturation factor gamma isoform 2
NM_001411106.1 NP_001398035.1 glia maturation factor gamma isoform 3
NM_004877.4 NP_004868.1 glia maturation factor gamma isoform 1

GMFG 蛋白结构

Cofilin_ADF

Cofilin_ADF: Cofilin/tropomyosin-type actin-binding protein (13 - 138)

  • 0
  • 100
  • 142 a.a.
蛋白主名 其他名称

glia maturation factor gamma

重组 GMFG 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76367 GMFG Protein, Human (His) O60234 (S2-R142) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GMFG RGD RGD:620506
Canis familiaris GMFG VGNC VGNC:53720
Macaca mulatta GMFG VGNC VGNC:73080
Mus musculus GMFG MGD MGI:1927135
Bos taurus GMFG VGNC VGNC:29435
Others GMFG NCBI