2. GPCR/G Protein
  3. GHSR
  4. Ghrelin receptor full agonist-2

Ghrelin receptor full agonist-2 (compound 12j) 是一种高效的 Ghrelin 受体 激动剂。

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Ghrelin receptor full agonist-2 Chemical Structure

Ghrelin receptor full agonist-2 Chemical Structure

CAS No. : 2602452-73-1

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Ghrelin receptor full agonist-2 相关抗体

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GHSR1a

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ghrelin receptor full agonist-2 (compound 12j) is a highly potent Ghrelin receptor full agonist.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
0.442 nM
Compound: 12j
Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF assay
Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF assay
[PMID: 32787075]
HEK293 EC50
0.9 nM
Compound: 12j
Agonist activity at dog GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins in presence of LiCl by HTRF assay
Agonist activity at dog GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 60 mins in presence of LiCl by HTRF assay
[PMID: 32787075]
分子量

558.05

Formula

C26H28ClN5O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ghrelin receptor full agonist-2 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ghrelin receptor full agonist-22602452-73-1Ghrelin receptor full agonist2Ghrelin receptor full agonist 2GHSRGrowth hormone secretagogue receptorGhrelin receptorInhibitorinhibitorinhibit

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