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GSK2226649A(compound 2) 是一种新型卫星细胞增殖和增强损伤肌肉修复的激活剂。

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GSK2226649A Chemical Structure

GSK2226649A Chemical Structure

CAS No. : 1848232-20-1

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  • 生物活性

  • 参考文献

生物活性

GSK2226649A (compound 2) is a novel activator of satellite cell proliferation and enhanced repair of damaged muscle[1].

体外研究
(In Vitro)

GSK2226649A(compound 2) (0.1-10μM) 可以剂量依赖性促进肌肉干细胞增殖,可有效加速骨骼肌损伤体内小鼠模型中受损骨骼肌的修复[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

The pharmacokinetic parameters of GSK2226649A(compound 2) in mice

Dose(mg) route Cmax(ng/mL) Tmax(hrs) T1/2(hrs) AUC0-inf(h*ng/mL)
30 oral 1384 0.5 1.6 1720
30 SC 1783 1.0 6.1 12077

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

378.81

Formula

C15H12ClFN6OS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

GSK2226649A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
GSK2226649A
目录号:
HY-103074
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