2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Iberiotoxin TFA

Iberiotoxin (TFA) 是一种选择性的高电导率 Ca2+ 激活的 K+ 通道 (Ca2+-activated K+ channel) 抑制剂，Kd 约为 1 nM。Iberiotoxin (TFA) 不阻断其他类型的电压依赖性离子通道。

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Custom Peptide Synthesis

Iberiotoxin TFA Chemical Structure

Iberiotoxin TFA Chemical Structure

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规格 价格 是否有货 数量
100 μg ￥3800
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Other Forms of Iberiotoxin TFA:

Iberiotoxin TFA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Iberiotoxin (TFA) is a selective high conductance high conductance Ca2+-activated K+ channel inhibitor with a Kd of ~1 nM. Iberiotoxin (TFA) does not block other types of voltage-dependent ion channels[1][2][3].

IC50 & Target

Kd: 1 nM (Ca2+-activated K+ channel)[1][3]
分子量

4230.85 (free base)

Formula

C179H274N50O55S7.xC2HF3O2
性状

固体

颜色

White to off-white

Sequence

{Glp}-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln (Disulfide bridge:Cys7-Cys28,Cys13-Cys33,Cys17-Cys35)
Sequence Shortening

{Glp}-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ (Disulfide bridge:Cys7-Cys28,Cys13-Cys33,Cys17-Cys35)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Iberiotoxin TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IberiotoxinPotassium ChannelKcsAion channelbovine aortic smooth musclechronic heart failureInhibitorinhibitorinhibit

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产品名称：
Iberiotoxin TFA
目录号：
HY-P0190A
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