1. TGF-beta/Smad
  2. TGF-β Receptor
  3. KRFK TFA

KRFK TFA 是来源于 TSP-1 的多肽,能够激活 TGF-β。KRFK TFA 促进 TGF-β 介导的信号传导及其下游作用,独立于血小板反应蛋白 TSP 受体,如 CD47 和 CD36。KRFK TFA 可用于可用于慢性眼表炎性疾病的研究。

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Custom Peptide Synthesis

KRFK TFA Chemical Structure

KRFK TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
5 mg ¥312
In-stock
10 mg ¥500
In-stock
25 mg ¥850
In-stock
50 mg ¥1380
In-stock
100 mg ¥2200
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of KRFK TFA:

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KRFK TFA, a peptide derived from TSP-1, can activate TGF-β. KRFK TFA promotes TGF-β-mediated signaling and its downstream role, independent of thrombospondin (TSP) receptors such as CD47 and CD36. KRFK TFA can be used for chronic ocular surface inflammatory disorders reseach[1].

IC50 & Target

TGF-β[1]

体外研究
(In Vitro)

KRFK TFA (50 μM; 24 h) 激活 TGF-β 的分泌,降低 TSP-1 缺陷骨髓源性树突状细胞 (BMDCs) 中 DC 成熟标记物的表达[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

KRFK TFA (单只眼用药 5 μg/5 μL; 单剂量) 显著预防 TSP-1-/- 小鼠慢性眼表炎症的发生[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

577.73 (free base)

Formula

C27H47N9O5.xC2HF3O2

性状

固体

颜色

White to off-white

Sequence

Lys-Arg-Phe-Lys

Sequence Shortening

KRFK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : ≥ 100 mg/mL

* "≥" means soluble, but saturation unknown.

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

KRFK TFA 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KRFK TFA
目录号:
HY-P3970A
需求量: