2. Immunology/Inflammation
  3. Complement System
  4. Lampalizumab

Lampalizumab  (Synonyms: RG 7417; TNX 234; Anti-CFD Recombinant Antibody)

目录号: HY-P99298 纯度: 99.46%
COA

摩尔计算器

Lampalizumab (RG 7417) 是一种人源单克隆抗体，靶向补体通路中的补体因子 D (Factor D)。Lampalizumab 可结合外位点，立体阻断因子 B 进入活性位点。Lampalizumab 可用于老年性黄斑变性 (AMD) 研究。

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Lampalizumab Chemical Structure

Lampalizumab Chemical Structure

CAS No. : 1278466-20-8

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规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9000
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Lampalizumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research[1][2].

IC50 & Target

Factor D[1]
体内研究
(In Vivo)

Lampalizumab 经静脉注射给食蟹猴后，5小时内血清因子D水平增加近10倍，有效中和了其抑制活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

143.8 (kDa)

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lampalizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lampalizumab1278466-20-8RG 7417 TNX 234 Anti-CFD Recombinant AntibodyRG7417RG-7417TNX234TNX 234TNX-234Complement SystemFactor Dage-related macular degenerationAMDmonoclonal antibodycomplement pathwayInhibitorinhibitorinhibit

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