2. Cell Cycle/DNA Damage Stem Cell/Wnt Cytoskeleton TGF-beta/Smad
  3. LIM Kinase (LIMK) ROCK
  4. LIMK-IN-1

LIMK-IN-1  (Synonyms: 化合物LIMK-IN-22J)

目录号: HY-14227
产品使用指南

摩尔计算器

LIMK-IN-1 是一种 LIM-Kinase (LIMK) 抑制剂，对 LIMK1 和 LIMK2 的 IC50 分别为 0.5 nM 和 0.9 nM。LIMK-IN-1 可用于高眼压和相关的青光眼研究。

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LIMK-IN-1 Chemical Structure

LIMK-IN-1 Chemical Structure

CAS No. : 1116571-01-7

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
2 mg ￥709
1 周
5 mg   询价  
10 mg   询价  

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Customer Review

LIMK-IN-1 相关抗体

Top Publications Citing Use of Products

查看 LIM Kinase (LIMK) 亚型特异性产品:

查看所有亚型
LIMK1 LIMK2

查看 ROCK 亚型特异性产品:

查看所有亚型
ROCK ROCK1 ROCK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1].

IC50 & Target[1]

LIMK1

0.9 nM (IC50)

LIMK2

0.5 nM (IC50)

ROCK1

260 nM (IC50)

ROCK2

2700 nM (IC50)

体外研究
(In Vitro)

LIMK-IN-1 (Compound 14) (100 nM) 在猪眼灌注测定中使流出系数增加约 30%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LIMK-IN-1 相关抗体:
分子量

453.34

Formula

C20H21BrN8
CAS 号
中文名称

化合物LIMK-IN-22J
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LIMK-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LIMK-IN-11116571-01-7化合物LIMK-IN-22JLIM Kinase (LIMK)ROCKLIMKsRho-associated protein kinaseRho-associated kinaseRho-kinaseROKLIM-Kinase 2 InhibitorsOcular HypertensionAssociated GlaucomaInhibitorinhibitorinhibit

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