1. Academic Validation
  2. Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum

Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum

  • Molecules. 2011 May 26;16(6):4371-8. doi: 10.3390/molecules16064371.
Wen-Wei Fu 1 Jin-Nan Fu Wen-Meng Zhang Li-Xin Sun Yue-Hu Pei Ping Liu
Affiliations

Affiliation

  • 1 Institute of Liver Diseases, Shanghai Shuguang Hospital, Shanghai 201203, China. fuwenwei@yahoo.com
Abstract

A new unusual minor triterpenoid saponin, platycoside O (1), was isolated from the 75% EtOH extract obtained from the roots of Platycodon grandiflorum, together with four known saponins: platycoside M-3 (2), platycoside J (3), platycoside F (4) and platycoside B (5). The structure of 1 was determined as 3-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-24-methoxyl, 24-oxo-28-oic acid 28-O-β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside on the basis of spectral analysis and chemical evidence.

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