2. Academic Validation
  3. OPA1 and Angiogenesis: Beyond the Fusion Function

OPA1 and Angiogenesis: Beyond the Fusion Function

  • Cell Metab. 2020 May 5;31(5):886-887. doi: 10.1016/j.cmet.2020.04.014.
Max-Hinderk Schuler 1,  Adam L Hughes 2
Affiliations

Affiliations

  • 1 Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
  • 2 Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Electronic address: hughes@biochem.utah.edu.
PMID: 32375059 DOI: 10.1016/j.cmet.2020.04.014
Abstract

In this issue of Cell Metabolism, Herkenne et al. (2020) show that the mitochondrial fusion protein OPA1 promotes angiogenesis independent of its function in mitochondrial dynamics, identifying a key new therapeutic target to prevent vascular growth during development and tumor formation.

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