2. Peptides
  3. Semax

Semax 是一种促神经保护肽，可用于脑卒中研究。

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Custom Peptide Synthesis

Semax Chemical Structure

Semax Chemical Structure

CAS No. : 80714-61-0

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Semax 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Semax is a nootropic neuroprotective peptide. Semax can be used in the research of brain stroke[1][2].

体外研究
(In Vitro)

Semax (25 μM and 100 μM, 48 h) reduces the Abeta oligomers (100 μM) levels[2].
Semax (100 nM) increase survival of cholinergic basal forebrain neurons[3].
Semax (100 nM) stimulates activity of choline acetyltransferase in dissociated basal forebrain tissue culture[3].
Semax (10 μM, 24 h) stimulates the synthesis of brain-derived neurotrophic factor (BDNF) in astrocytes cultured from rat basal forebrain[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Semax 相关抗体:
体内研究
(In Vivo)

Semax (100 μg/kg, i.p.) promotes the formation and functioning of the vascular system in Ischemia (pMCAO) rats[1].
Semax (50 µg and 250 µg, 100 µL/kg, intranasal inhalation) increases levels of b BDNF protein in rat basal forebrain[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Ischemia (pMCAO) rats[1].
Dosage: 100 μg/kg
Administration: Intraperitoneal injections (i.p.), performed 15 min, 1, 4 and 8 h after permanent middle cerebral artery occlusion (pMCAO).
Result: Increased the immune response (upregulation of transcripts).
Animal Model: Rats[5]
Dosage: 50 µg, 250 µg, 100 µL/kg
Administration: Intranasal inhalation
Result: Increased levels of brain-derived neurotrophic factor (BDNF) protein in rat basal forebrain.
分子量

813.92

Formula

C37H51N9O10S
CAS 号
Sequence

Met-Glu-His-Phe-Pro-Gly-Pro
Sequence Shortening

MEHFPGP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Semax80714-61-0OthersIschemiaBDNFastrocytesnootropicneuroprotectiveAbetaInhibitorinhibitorinhibit

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