Methoxsalen (Synonyms: 甲氧沙林; 8-Methoxypsoralen; Xanthotoxin; 8-MOP)

目录号: HY-30151 纯度: 99.97%: Data Sheet SDS COA 产品使用指南
FAQs
技术支持

Methoxsalen (8-Methoxypsoralen) 是呋喃香豆素化合物，可用于补骨脂，用于研究牛皮癣，湿疹，白癜风和一些暴露在阳光下的皮肤淋巴瘤，是P450抑制剂。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Methoxsalen Chemical Structure

CAS No. : 298-81-7

1. 客户无需承担相应的运输费用。

2. 同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

可免费申领三个不同产品的试用装。

3. 试用装只面向终端客户。

规格	价格	是否有货
10 mM * 1 mL in DMSO	￥500	In-stock
500 mg	￥350	In-stock
1 g	￥420	In-stock
5 g	￥1340	In-stock
10 g	￥2140	In-stock
25 g	￥3850	In-stock
50 g	￥5390	In-stock
> 100 g		询价

or 大包装询价

* Please select Quantity before adding items.

Customer Review

Other Forms of Methoxsalen:

Methoxsalen-d₃ In-stock
Methoxsalen (Standard) 询价

MCE 顾客使用本产品发表的 14 篇科研文献

Methoxsalen 相关产品

•相关化合物库:

•同靶点产品:

•同靶点蛋白产品:

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型

CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

生物活性
纯度 & 产品资料
参考文献

生物活性

Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
A-431	IC₅₀	2.48 μM Compound: 8-MOP	Compound was evaluated for cell growth inhibition against A 431 cell line by irradiation in the presence of examined compound Compound was evaluated for cell growth inhibition against A 431 cell line by irradiation in the presence of examined compound	[PMID: 8893844]
A-431	IC₅₀	25 μM Compound: 8-MOP	Antiproliferative activity against human A431 cells incubated for 1 hr with inhibitor followed by UV irradiation measured after 24 hrs by trypan blue dye assay Antiproliferative activity against human A431 cells incubated for 1 hr with inhibitor followed by UV irradiation measured after 24 hrs by trypan blue dye assay	[PMID: 22537681]
A-431	IC₅₀	> 30 μM Compound: 8-MOP	Antiproliferative activity against human A431 cells after 24 hrs by trypan blue dye assay Antiproliferative activity against human A431 cells after 24 hrs by trypan blue dye assay	[PMID: 22537681]
AGS	IC₅₀	> 100 μM Compound: Xanthotoxin	Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 28947149]
HCT-116	IC₅₀	> 100 μM Compound: 6	Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay	[PMID: 23746477]
HL-60	IC₅₀	0.75 μM Compound: 8-MOP	Compound was evaluated for cell growth inhibition against HL 60 cell line by irradiation in the presence of examined compound Compound was evaluated for cell growth inhibition against HL 60 cell line by irradiation in the presence of examined compound	[PMID: 8893844]
HL-60	IC₅₀	1.2 μM Compound: 8-MOP	Cytotoxicity against HL-60 (human fibrosarcoma) cell line at 3.2 joule/cm2 UVA dose Cytotoxicity against HL-60 (human fibrosarcoma) cell line at 3.2 joule/cm2 UVA dose	[PMID: 15837311]
HL-60	IC₅₀	1.2 μM Compound: 8-MOP	Photocytotoxicity against human HL-60 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human HL-60 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
HL-60	IC₅₀	1.4 μM Compound: 8-MOP	Cytotoxicity against HL-60 (human fibrosarcoma) cell line at 2.5 joule/cm2 UVA dose Cytotoxicity against HL-60 (human fibrosarcoma) cell line at 2.5 joule/cm2 UVA dose	[PMID: 15837311]
HL-60	IC₅₀	1.4 μM Compound: 8-MOP	Photocytotoxicity against human HL-60 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human HL-60 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
HL-60	IC₅₀	5.4 mM Compound: 8-MOP (8-Methoxypsoralen)	In vitro antiproliferative activity against human promyelocytic (HL-60) cells In vitro antiproliferative activity against human promyelocytic (HL-60) cells	[PMID: 10673096]
HL-60	IC₅₀	5.4 μM Compound: 8 -MOP	Antiproliferative activity against HL-60 (human promyelocytic leukemic cells) after exposure to UV light Antiproliferative activity against HL-60 (human promyelocytic leukemic cells) after exposure to UV light	[PMID: 12930143]
HL-60	IC₅₀	5.4 μM Compound: 8-MOP	The compound was tested in vitro for growth inhibition against HL-60(human promyelocytic leukemia) cell line in the presence of UVA(ultra violet A irradiated) The compound was tested in vitro for growth inhibition against HL-60(human promyelocytic leukemia) cell line in the presence of UVA(ultra violet A irradiated)	[PMID: 10543884]
HL-60	IC₅₀	5.4 μM Compound: 8-MOP	Compound was evaluated for its antiproliferative activity after UVA irradiation on human tumor HL-60 cell line Compound was evaluated for its antiproliferative activity after UVA irradiation on human tumor HL-60 cell line	[PMID: 11965365]
HL-60	IC₅₀	5.4 μM Compound: 8-MOP	Antiproliferative activity against HL60 cells in presence of 0.789 J/cm2 UVA light Antiproliferative activity against HL60 cells in presence of 0.789 J/cm2 UVA light	[PMID: 16821791]
HL-60	IC₅₀	5.4 μM Compound: 8-MOP	Cytotoxicity against human HL60 cells after 24 hrs by trypan blue assay in presence of 0.789 J cm-2 of UVA light Cytotoxicity against human HL60 cells after 24 hrs by trypan blue assay in presence of 0.789 J cm-2 of UVA light	[PMID: 20615713]
HL-60	IC₅₀	> 20 μM Compound: 8 -MOP	Antiproliferative activity against HL-60 (human promyelocytic leukemic cells) in dark condition Antiproliferative activity against HL-60 (human promyelocytic leukemic cells) in dark condition	[PMID: 12930143]
HL-60	IC₅₀	> 20 μM Compound: 8-MOP	The compound was tested in vitro for growth inhibition against HL-60(human promyelocytic leukemia) cell line in the dark The compound was tested in vitro for growth inhibition against HL-60(human promyelocytic leukemia) cell line in the dark	[PMID: 10543884]
HL-60	IC₅₀	> 20 μM Compound: 8-MOP	Antiproliferative activity against HL60 cells in dark Antiproliferative activity against HL60 cells in dark	[PMID: 16821791]
HL-60	IC₅₀	> 20 μM Compound: 8-MOP	Cytotoxicity against human HL60 cells treated under dark condition after 24 hrs by trypan blue assay Cytotoxicity against human HL60 cells treated under dark condition after 24 hrs by trypan blue assay	[PMID: 20615713]
HL-60	IC₅₀	> 20 μM Compound: 8-MOP	Cytotoxicity against human HL60 cells treated under dark condition after 72 hrs by trypan blue assay Cytotoxicity against human HL60 cells treated under dark condition after 72 hrs by trypan blue assay	[PMID: 20615713]
HT-1080	IC₅₀	1.5 μM Compound: 8-MOP	Inhibition of cell growth after irradiation at UVA dose of 6.5 J/cmE-2 in HT1080 human fibrosarcoma cell line Inhibition of cell growth after irradiation at UVA dose of 6.5 J/cmE-2 in HT1080 human fibrosarcoma cell line	[PMID: 12873520]
HT-1080	IC₅₀	1.9 μM Compound: 8-MOP	Photocytotoxicity against human HT1080 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human HT1080 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
HT-1080	IC₅₀	2.1 μM Compound: 8-MOP	Inhibition of cell growth after irradiation at UVA dose of 3.2 J/cmE-2 in HT1080 human fibrosarcoma cell line Inhibition of cell growth after irradiation at UVA dose of 3.2 J/cmE-2 in HT1080 human fibrosarcoma cell line	[PMID: 12873520]
HT-1080	IC₅₀	7.8 μM Compound: 8-MOP	Inhibition of cell growth after irradiation at UVA dose of 2.6 J/cmE-2 in HT1080 human fibrosarcoma cell line Inhibition of cell growth after irradiation at UVA dose of 2.6 J/cmE-2 in HT1080 human fibrosarcoma cell line	[PMID: 12873520]
HT-1080	IC₅₀	7.8 μM Compound: 8-MOP	Photocytotoxicity against human HT1080 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human HT1080 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
HT-29	IC₅₀	> 100 μM Compound: 6	Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay Cytotoxicity against human HT-29 cells after 96 hrs by MTT assay	[PMID: 23746477]
HeLa	IC₅₀	10 mM Compound: 8-MOP (8-Methoxypsoralen)	In vitro antiproliferative activity against human cervix adenocarcinoma (HeLa) cells In vitro antiproliferative activity against human cervix adenocarcinoma (HeLa) cells	[PMID: 10673096]
HeLa	IC₅₀	10 μM Compound: 8 -MOP	Antiproliferative activity against HeLa (human cervix adenocarcinoma cells) after exposure to UV light Antiproliferative activity against HeLa (human cervix adenocarcinoma cells) after exposure to UV light	[PMID: 12930143]
HeLa	IC₅₀	10 μM Compound: 8-MOP	The compound was tested in vitro for growth inhibition against HeLa(human cervix adenocarcinoma) cell line in the presence of UVA(ultra violet A irradiated) The compound was tested in vitro for growth inhibition against HeLa(human cervix adenocarcinoma) cell line in the presence of UVA(ultra violet A irradiated)	[PMID: 10543884]
HeLa	IC₅₀	10 μM Compound: 8-MOP	Compound was evaluated for its antiproliferative activity after UVA irradiation on human tumor HeLa cell line Compound was evaluated for its antiproliferative activity after UVA irradiation on human tumor HeLa cell line	[PMID: 11965365]
HeLa	IC₅₀	10 μM Compound: 8-MOP	Antiproliferative activity against HeLa cells in presence of 0.789 J/cm2 UVA light Antiproliferative activity against HeLa cells in presence of 0.789 J/cm2 UVA light	[PMID: 16821791]
HeLa	IC₅₀	10 μM Compound: 8-MOP	Photo-antiproliferative activity against human HeLa cells exposed to 365 nm, 0.793 Jcm'-2 UVA light Photo-antiproliferative activity against human HeLa cells exposed to 365 nm, 0.793 Jcm'-2 UVA light	[PMID: 19359172]
HeLa	IC₅₀	10 μM Compound: 8-MOP	Antiproliferative activity against human HeLa cells incubated for 1 hr with inhibitor followed by UV irradiation measured after 24 hrs by trypan blue dye assay Antiproliferative activity against human HeLa cells incubated for 1 hr with inhibitor followed by UV irradiation measured after 24 hrs by trypan blue dye assay	[PMID: 22537681]
HeLa	IC₅₀	3.16 μM Compound: 8-MOP	Compound was evaluated for cell growth inhibition against HeLa cell line by irradiation in the presence of examined compound Compound was evaluated for cell growth inhibition against HeLa cell line by irradiation in the presence of examined compound	[PMID: 8893844]
HeLa	IC₅₀	7.6 μg/mL Compound: Xanthotoxin	Antitumor activity against human HeLa cells after 72 hrs by MTS assay Antitumor activity against human HeLa cells after 72 hrs by MTS assay	[PMID: 19217697]
HeLa	IC₅₀	> 20 μM Compound: 8 -MOP	Antiproliferative activity against HeLa (human cervix adenocarcinoma cells) in dark condition Antiproliferative activity against HeLa (human cervix adenocarcinoma cells) in dark condition	[PMID: 12930143]
HeLa	IC₅₀	> 20 μM Compound: 8-MOP	The compound was tested in vitro for growth inhibition against HeLa(human cervix adenocarcinoma) cell line in the dark The compound was tested in vitro for growth inhibition against HeLa(human cervix adenocarcinoma) cell line in the dark	[PMID: 10543884]
HeLa	IC₅₀	> 20 μM Compound: 8-MOP	Antiproliferative activity against HeLa cells in dark Antiproliferative activity against HeLa cells in dark	[PMID: 16821791]
HeLa	IC₅₀	> 20 μM Compound: 8-MOP	Photo-antiproliferative activity against human HeLa cells under dark condition Photo-antiproliferative activity against human HeLa cells under dark condition	[PMID: 19359172]
HeLa	IC₅₀	> 30 μM Compound: 8-MOP	Antiproliferative activity against human HeLa cells after 24 hrs by trypan blue dye assay Antiproliferative activity against human HeLa cells after 24 hrs by trypan blue dye assay	[PMID: 22537681]
Jurkat	IC₅₀	1.2 μM Compound: 8-MOP	Photocytotoxicity against human JURKAT cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human JURKAT cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
Jurkat	IC₅₀	1.2 μM Compound: 8MOP	Phototoxicity against human Jurkat cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay Phototoxicity against human Jurkat cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay	[PMID: 19230658]
Jurkat	IC₅₀	> 20 μM Compound: 8MOP	Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay	[PMID: 19230658]
K562	IC₅₀	> 20 μM Compound: 8MOP	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 19230658]
L02	IC₅₀	> 100 μM Compound: Xanthotoxin	Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay	[PMID: 28947149]
LoVo	IC₅₀	0.4 μM Compound: 8-MOP	Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 6.5 joule/cm2 UVA dose Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 6.5 joule/cm2 UVA dose	[PMID: 15837311]
LoVo	IC₅₀	0.7 μM Compound: 8-MOP	Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 3.2 joule/cm2 UVA dose Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 3.2 joule/cm2 UVA dose	[PMID: 15837311]
LoVo	IC₅₀	0.7 μM Compound: 8-MOP	Photocytotoxicity against human LoVo cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human LoVo cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
LoVo	IC₅₀	0.7 μM Compound: 8MOP	Phototoxicity against human LoVo cells exposed to irradiation with 3.75 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay Phototoxicity against human LoVo cells exposed to irradiation with 3.75 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay	[PMID: 19230658]
LoVo	IC₅₀	1.1 μM Compound: 8-MOP	Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 2.5 joule/cm2 UVA dose Cytotoxicity against LoVo (human intestinal adenocarcinoma) cell line at 2.5 joule/cm2 UVA dose	[PMID: 15837311]
LoVo	IC₅₀	1.1 μM Compound: 8-MOP	Photocytotoxicity against human LoVo cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human LoVo cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
LoVo	IC₅₀	1.1 μM Compound: 8MOP	Phototoxicity against human LoVo cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay Phototoxicity against human LoVo cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay	[PMID: 19230658]
LoVo	IC₅₀	> 20 μM Compound: 8MOP	Cytotoxicity against human LoVo cells after 72 hrs by MTT assay Cytotoxicity against human LoVo cells after 72 hrs by MTT assay	[PMID: 19230658]
MES-SA/Dx5	IC₅₀	3.1 μM Compound: 6	Cytotoxicity against human MES-SA/Dx5 cells after 96 hrs by MTT assay Cytotoxicity against human MES-SA/Dx5 cells after 96 hrs by MTT assay	[PMID: 23746477]
NCTC-2544	IC₅₀	0.9 μM Compound: 8-MOP	Photocytotoxicity against human NCTC 2544 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human NCTC 2544 cells treated 30 mins before 3.75 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
NCTC-2544	IC₅₀	5.5 μM Compound: 8-MOP	Photocytotoxicity against human NCTC 2544 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay Photocytotoxicity against human NCTC 2544 cells treated 30 mins before 2.5 J/cm'2 UVA irradiation measured after 72 hrs by MTT assay	[PMID: 18951030]
NCTC-2544	IC₅₀	5.5 μM Compound: 8MOP	Phototoxicity against human NCTC-2544 cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay Phototoxicity against human NCTC-2544 cells exposed to irradiation with 2.5 J/cm'2 UVA light prior to 72 hrs drug exposure by MTT assay	[PMID: 19230658]
NCTC-2544	IC₅₀	> 20 μM Compound: 8MOP	Cytotoxicity against human NCTC-2544 cells after 72 hrs by MTT assay Cytotoxicity against human NCTC-2544 cells after 72 hrs by MTT assay	[PMID: 19230658]
PAM212	IC₅₀	0.1 μM Compound: 2; 8-MOP	Phototoxicity against mouse PAM212 cells assessed as cell growth inhibition preincubated for 30 mins followed by 1.28 J/cm2 UV light exposure and measured after 5 days by coulter counting method Phototoxicity against mouse PAM212 cells assessed as cell growth inhibition preincubated for 30 mins followed by 1.28 J/cm2 UV light exposure and measured after 5 days by coulter counting method	[PMID: 30638875]
PAM212	IC₅₀	> 100 μM Compound: 2; 8-MOP	Dark toxicity against mouse PAM212 cells assessed as cell growth inhibition incubated for 30 mins under dark condition measured after 5 days by coulter counting method Dark toxicity against mouse PAM212 cells assessed as cell growth inhibition incubated for 30 mins under dark condition measured after 5 days by coulter counting method	[PMID: 30638875]
PAM212	IC₅₀	> 100 μM Compound: 2; 8-MOP	Dark toxicity against mouse PAM212 cells assessed as cell growth inhibition incubated for 5 days under dark condition by coulter counting method Dark toxicity against mouse PAM212 cells assessed as cell growth inhibition incubated for 5 days under dark condition by coulter counting method	[PMID: 30638875]
PANC-1	IC₅₀	83.3 μM Compound: 6	Cytotoxicity against human PANC1 cells after 96 hrs by MTT assay Cytotoxicity against human PANC1 cells after 96 hrs by MTT assay	[PMID: 23746477]
Panel leukemia (Carcinoma cell lines)	IC₅₀	100 μM Compound: 1	In vitro photocytotoxicity is evaluated against human chronic myeloid leukemia cells grown in culture irradiated at 366 nM In vitro photocytotoxicity is evaluated against human chronic myeloid leukemia cells grown in culture irradiated at 366 nM	[PMID: 8164263]
Panel leukemia (Carcinoma cell lines)	IC₅₀	> 100 μM Compound: 1	In vitro photocytotoxicity is evaluated against human chronic myeloid leukemia cells grown in culture under the dark conditions In vitro photocytotoxicity is evaluated against human chronic myeloid leukemia cells grown in culture under the dark conditions	[PMID: 8164263]
Raji	IC₅₀	490 molar ratio Compound: 7	Inhibition of TPA-induced EBV-early antigen activation in human Raji cells Inhibition of TPA-induced EBV-early antigen activation in human Raji cells	[PMID: 16441065]

体内研究
(In Vivo)

Methoxsalen（15mg/kg，腹腔注射，单剂量）增加尼古丁的 C_max，延长血浆尼古丁半衰期（增加四倍），降低其清除率（减少六倍），并增加其 AUC^{[ 1]}。
Methoxsalen（15mg/kg，腹腔注射，单剂量）可增强口服尼古丁的药理作用（体温和镇痛）^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male adult ICR mice^[1]
Dosage:	15 mg/kg
Administration:	Intraperitoneal injection (i.p.), single dose
Result:	Increased nicotine plasma levels were still above 10ng/ml at 6hr. Induced nicotine’s antinociceptive and hypothermic lasted close to 6 and 24 hr.

Clinical Trial

分子量

216.19

Formula

C₁₂H₈O₄

CAS 号

298-81-7

性状

固体

颜色

White to light yellow

中文名称

花椒毒素；8-甲氧基补骨酯；甲氧基补骨脂素；8-甲氧基补骨脂素；甲氧沙林；8-甲氧补骨脂素；甲氧补骨脂素；8-甲氧补骨脂

结构分类

初始来源

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

溶解性数据

细胞实验：

DMSO 中的溶解度 : 50 mg/mL (231.28 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

H₂O 中的溶解度 : < 0.1 mg/mL (insoluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.6256 mL	23.1278 mL	46.2556 mL
5 mM	0.9251 mL	4.6256 mL	9.2511 mL
10 mM	0.4626 mL	2.3128 mL	4.6256 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物实验：

请根据您的实验动物和给药方式选择适当的溶解方案。

以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；
以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (11.56 mM); 澄清溶液

此方案可获得 ≥ 2.5 mg/mL（饱和度未知）的澄清溶液。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；再向上述体系中加入 50 μL Tween-80，混合均匀；然后再继续加入 450 μL 生理盐水定容至 1 mL。
生理盐水的配制：将 0.9 g 氯化钠，溶解于 ddH₂O 并定容至 100 mL，可以得到澄清透明的生理盐水溶液。
方案二

请依序添加每种溶剂： 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (11.56 mM); 澄清溶液

此方案可获得 ≥ 2.5 mg/mL（饱和度未知）的澄清溶液，此方案实验周期在半个月以上的动物实验酌情使用。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

请输入您的动物体内配方组成：

DMSO +

Tween-80 +

Saline

如果您的动物是免疫缺陷鼠或者体弱鼠，建议 DMSO 中的在最后工作液体系中的占比尽量不超过 2%。

方案所需 助溶剂 包括：DMSO，，均可在 MCE 网站选购。，Tween 80，均可在 MCE 网站选购。

计算结果

工作液所需浓度 : mg/mL

储备液配制方法 : mg 药物溶于 μL DMSO（母液浓度为 mg/mL）。

您所需的储备液浓度超过该产品的实测溶解度，以下方案仅供参考，如有需要，请与 MCE 中国技术支持联系。

动物实验体内工作液的配制方法 : 取 μL DMSO 储备液，加入 μL 。 μL ，混合均匀至澄清，再加 μL Tween 80，混合均匀至澄清，再加 μL 生理盐水。

连续给药周期超过半月以上，请谨慎选择该方案。

请确保第一步储备液溶解至澄清状态，从左到右依次添加助溶剂。您可采用超声加热（超声清洗仪，建议频次 20-40 kHz），涡旋吹打等方式辅助溶解。

纯度 & 产品资料

纯度: 99.98%

选择批次：

Data Sheet (637 KB) SDS (557 KB)

COA (290 KB) HNMR (115 KB) RP-HPLC (147 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16(1):18-25. [Content Brief]

Methoxsalen 相关分类

完整储备液配制表

可选溶剂	浓度溶剂体积质量	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.6256 mL	23.1278 mL	46.2556 mL	115.6390 mL
	5 mM	0.9251 mL	4.6256 mL	9.2511 mL	23.1278 mL
	10 mM	0.4626 mL	2.3128 mL	4.6256 mL	11.5639 mL
	15 mM	0.3084 mL	1.5419 mL	3.0837 mL	7.7093 mL
	20 mM	0.2313 mL	1.1564 mL	2.3128 mL	5.7820 mL
	25 mM	0.1850 mL	0.9251 mL	1.8502 mL	4.6256 mL
	30 mM	0.1542 mL	0.7709 mL	1.5419 mL	3.8546 mL
	40 mM	0.1156 mL	0.5782 mL	1.1564 mL	2.8910 mL
	50 mM	0.0925 mL	0.4626 mL	0.9251 mL	2.3128 mL
	60 mM	0.0771 mL	0.3855 mL	0.7709 mL	1.9273 mL
	80 mM	0.0578 mL	0.2891 mL	0.5782 mL	1.4455 mL
	100 mM	0.0463 mL	0.2313 mL	0.4626 mL	1.1564 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methoxsalen298-81-78-Methoxypsoralen Xanthotoxin 8-MOP花椒毒素8-甲氧基补骨酯甲氧基补骨脂素8-甲氧基补骨脂素甲氧沙林8-甲氧补骨脂素甲氧补骨脂素8-甲氧补骨脂Cytochrome P450CYPsInhibitorinhibitorinhibit

产品名称：			* 需求量：
* 客户姓名：			* Email：
* 电话：			* 公司或机构名称：
留言给我们：

产品名称：			* Lot #：
* 客户姓名：			* Email：
电话：			* 部门：
* 公司或机构名称：
留言给我们：

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

Methoxsalen (Synonyms: 甲氧沙林; 8-Methoxypsoralen; Xanthotoxin; 8-MOP)

Customer Review

Other Forms of Methoxsalen:

MCE 顾客使用本产品发表的 14 篇科研文献

Methoxsalen 相关产品

•相关化合物库:

•同靶点产品:

•同靶点蛋白产品:

查看 Cytochrome P450 亚型特异性产品:

生物活性

纯度 & 产品资料

参考文献

摩尔计算器

稀释计算器

Methoxsalen 相关分类

完整储备液配制表

Keywords:

您最近查看的产品:

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

Methoxsalen (Synonyms: 甲氧沙林; 8-Methoxypsoralen; Xanthotoxin; 8-MOP)

Customer Review

Other Forms of Methoxsalen:

Methoxsalen 相关抗体

MCE 顾客使用本产品发表的 14 篇科研文献

Methoxsalen 相关产品

•相关化合物库:

•同靶点产品:

•同靶点蛋白产品:

查看 Cytochrome P450 亚型特异性产品:

生物活性

纯度 & 产品资料

参考文献

摩尔计算器

稀释计算器

Methoxsalen 相关分类

完整储备液配制表

Keywords:

您最近查看的产品:

Request for HNMR Report

Request for HNMR Report

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z