2. Anti-infection
  3. Bacterial
  4. (-)-Cleistenolide

(-)-Cleistenolide  (Synonyms: Cleistenolide)

目录号: HY-N10391
产品使用指南

摩尔计算器

(-)-Cleistenolide 是一种 α,β- 不饱和 δ- 内酯，从Cleistochlamys kirkii Oliver 中分离得到。(-)-Cleistenolide 具有抗菌和抗肿瘤活性。

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(-)-Cleistenolide Chemical Structure

(-)-Cleistenolide Chemical Structure

CAS No. : 1003600-48-3

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(-)-Cleistenolide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity[1].

体外研究
(In Vitro)

(-)-Cleistenolide (compound 1) exhibits potent cytotoxicity against cancer cell lines and low cytotoxicity in normal cells MRC-5[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(-)-Cleistenolide 相关抗体:

Cell Cytotoxicity Assay

Cell Line: K562, HL-60, Jurkat, Raji, MCF-7, MDA-MB 231, HeLa, A549 and MRC-5[1]
Concentration: 0-100 μM
Incubation Time:
Result: Exhibited potent cytotoxicity against cancer cell lines with IC50s of 7.65 μM, 1.21 μM, 14.22 μM, 36.94 μM, 26.07 μM, 2.25 μM, 7.32 μM and 16.34 μM in K562, HL-60, Jurkat, Raji, MCF-7, MDA-MB 231, HeLa and A549, respectively; and had low cytotoxicity in normal cells MRC-5 with an IC50 over 100 μM.
分子量

362.33

Formula

C18H18O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(-)-Cleistenolide 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-Cleistenolide1003600-48-3CleistenolideBacterialAntibacteriaAntitumorCleistochlamys kirkiiMDA-MB 231HeLaA549Inhibitorinhibitorinhibit

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