1. Anti-infection
  2. SARS-CoV Virus Protease
  3. Mpro inhibitor N3 hemihydrate

Mpro inhibitor N3 hemihydrate 

目录号: HY-136149A 纯度: ≥98.0%
COA 产品使用指南

Mpro inhibitor N3 hemihydrate 是一种有效的 SARS-CoV-2 Mpro 抑制剂,对 SARS-CoV-2 的 EC50 为 16.77 μM。Mpro inhibitor N3 hemihydrate 特别抑制多种病毒的 Mpro,包括 SARS-CoV 和 MERS-CoV。Mpro inhibitor N3 hemihydrate 对 HCoV-229E、FIPV 和 MHV-A59 的抑制,IC50 分别为 4.0 μM、8.8 μM 和 2.7 μM。

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Mpro inhibitor N3 hemihydrate Chemical Structure

Mpro inhibitor N3 hemihydrate Chemical Structure

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规格 价格 是否有货 数量
5 mg ¥1390
In-stock
25 mg ¥5800
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC50 of 4.0 μM, 8.8 μM, and 2.7 μM, respectively[1][2].

IC50 & Target

EC50: 16.77 μM (SARS-CoV-2)[1]

体内研究
(In Vivo)

Mpro inhibitor N3 hemihydrate (0-0.64 μM) 能够穿透细胞抑制 IBV 病毒的复制,可能在胚胎感染初期[3]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

698.81

Formula

C35H50N6O9

性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

参考文献

Mpro inhibitor N3 hemihydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mpro inhibitor N3 hemihydrate
目录号:
HY-136149A
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