2. Cytoskeleton
  3. Integrin
  4. Odulimomab

Odulimomab  (Synonyms: anti-LFA1)

目录号: HY-P99765

摩尔计算器

Odulimomab (anti-LFA1) 是一种抗 LFA-1 单克隆抗体。Odulimomab 抑制 T 淋巴细胞增殖，对缺血再灌注损伤有保护作用。Odulimomab 可用于移植排斥反应和免疫疾病的研究。

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Odulimomab Chemical Structure

Odulimomab Chemical Structure

CAS No. : 159445-64-4

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Odulimomab 相关抗体

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Odulimomab (anti-LFA1) is an anti-LFA-1 monoclonal antibody. Odulimomab inhibits proliferation of T lymphocyte and shows protective effects against ischemia and reperfusion injury. Odulimomab can be used for the research of transplant rejection and immunological disease[1][2].

体外研究
(In Vitro)

Odulimomab 在体外抑制 T 淋巴细胞增殖，以及 T 和自然杀伤细胞 (NK) 的细胞毒性和抗体产生[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Odulimomab 相关抗体:
体内研究
(In Vivo)

Odulimomab (1.5 和 0.75 mg/kg；腹腔注射，第 1 次处理 1.5 mg/kg，然后每天注射 0.75 mg/kg) 对缺血和再灌注损伤有保护作用，对移植后肾功能有所修复[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cynomolgus Monkeys with renal damage ischemia and kidney autotransplantation[1]
Dosage: 1.5 and 0.75 mg/kg
Administration: Intraperitoneal injection; 1.5 mg/kg for the first dose and after pedicle clamping followed by daily injection of 0.75 mg/kg until sacrifice
Result: Decreased the creatinine level after ischemia and autotransplantation for 3 days and increased the potassium fraction reabsorption.
CAS 号
储存方式

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纯度 & 产品资料
参考文献

Odulimomab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Odulimomab159445-64-4anti-LFA1IntegrinT lymphocyteNKischemia and reperfusion injuryrenalmonkeyInhibitorinhibitorinhibit

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