2. Metabolic Enzyme/Protease
  3. Isocitrate Dehydrogenase (IDH)
  4. Oxalomalic acid trisodium

Oxalomalic acid trisodium  (Synonyms: Oxalomalate trisodium)

目录号: HY-131521
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Oxalomalic Acid (Oxalomalate) trisodium 是一种乌头酸酶 (aconitase) 和 NADP 依赖性异柠檬酸脱氢酶 (NADP-dependent isocitrate dehydrogenase) 抑制剂。Oxalomalic Acid trisodium 抑制脂多糖 (HY-D1056) 激活的 J774 巨噬细胞中亚硝酸盐的产生和 iNOS 蛋白的表达。

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Oxalomalic acid trisodium Chemical Structure

Oxalomalic acid trisodium Chemical Structure

CAS No. : 89304-26-7

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Oxalomalic acid trisodium 相关抗体

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  • 生物活性

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生物活性

Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages[1].

体外研究
(In Vitro)

Oxalomalic acid trisodium (2.2, 5 mM; 2+24 h) 可减少 J774 细胞中 LPS 诱导的亚硝酸盐产生和 iNOS 蛋白表达[1]。
Oxalomalic acid trisodium (5 mM; 6, 12 h) 对 LPS 刺激的 J774 巨噬细胞中 iNOS mRNA 的表达没有影响[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Oxalomalic acid trisodium 相关抗体:

Western Blot Analysis[1]

Cell Line: J774 cells
Concentration: 2.2, 5 mM (stimulated with LPS (1 μg/ml))
Incubation Time: 2+24 h
Result: Reduced in a significant and concentration-dependent manner nitrite production, reduced iNOS protein expression.
分子量

272.05

Formula

C6H3Na3O8
CAS 号
中文名称

Α-羟基-Β-草酰琥珀酸三钠
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oxalomalic acid trisodium 相关分类

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Keywords:

Oxalomalic acid trisodium89304-26-7Oxalomalate trisodiumΑ-羟基-Β-草酰琥珀酸三钠Isocitrate Dehydrogenase (IDH)LPSnitriteiNOS proteinJ774 cellsInhibitorinhibitorinhibit

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