2. GPCR/G Protein Apoptosis
  3. GnRH Receptor Apoptosis
  4. Ozarelix

Ozarelix (D-63153) 是一种 GnRH 拮抗剂。Ozarelix 诱导细胞凋亡并将细胞阻滞在 G2/M 期。Ozarelix 可用于前列腺癌的研究。

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Custom Peptide Synthesis

Ozarelix Chemical Structure

Ozarelix Chemical Structure

CAS No. : 295350-45-7

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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规格 是否有货
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Customer Review

Ozarelix 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer[1].

体外研究
(In Vitro)

Ozarelix (0-20 ng/mL, 72 h) inhibits PC3 and DU145 cell proliferation[1].
Ozarelix (0-20 ng/mL, 72 h) induces apoptosis in PC3 and DU145 cells[1].
Ozarelix (20 ng/mL, 72 h) triggers caspase 8-dependent caspase 3 activation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ozarelix 相关抗体:

Cell Proliferation Assay[1]

Cell Line: Serum-starved PC3 and DU145 cells
Concentration: 0, 5, 10, 20 ng/mL
Incubation Time: 0, 24, 48, 72, 96 h
Result: Inhibited cell proliferation in a dose and time-dependent manner.

Western Blot Analysis[1]

Cell Line: PC3 and DU145 cells
Concentration: 0, 5, 10, 20 ng/mL
Incubation Time: 72 h
Result: Increased the levels of p21 and p27 both in PC3 and DU145 cells.
Decreased levels of anti-apoptotic proteins such as Bcl2 and Bcl-Xl.
Upregulated Erk and p38MAPK activity.
Clinical Trial
分子量

1459.09

Formula

C72H96ClN17O14
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ozarelix 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ozarelix295350-45-7D-63153D63153D 63153GnRH ReceptorApoptosisGonadotropin releasing hormone receptorGNRHRCancerDU145PC3prostate cancerantiproliferationInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-16375
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