2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARδ agonist 9

PPARδ agonist 9 (compound 21) 是 PPARδ 激动剂 (EC50: 3.6 nM)。PPARδ agonist 9 具有体内效力，在小鼠中降低 MCP-1 的血清水平，显着抑制 LDLr-KO 模型的动脉粥样硬化进展 (抑制率: 50-60%)。

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PPARδ agonist 9 Chemical Structure

PPARδ agonist 9 Chemical Structure

CAS No. : 928023-21-6

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PPARδ agonist 9 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].

IC50 & Target

EC50:3.6 nM (PPARδ)[1]
分子量

569.04

Formula

C26H28ClF3N4O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PPARδ agonist 9 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARδ agonist 9928023-21-6PPARδ agonist9PPARδ agonist-9PPARPeroxisome proliferator-activated receptorsmetabolic diseasesatherosclerosisInhibitorinhibitorinhibit

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PPARδ agonist 9
目录号：
HY-149429
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