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PRO-F 是一种具有 ROS 清除能力的光活化 H2S 供体。PRO-F可被光激活产生荧光信号,用于实时跟踪释放的 H2S。PRO-F 激活不消耗内源性物质。在细胞内环境中递送 H2S,以保护细胞免受过度活性氧 (ROS) 引起的损伤。PRO-F 显示出对慢性伤口愈合的增强作用,在糖尿病模型中也得到探究。

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PRO-F Chemical Structure

PRO-F Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PRO-F is a photoactivable H2S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H2S. PRO-F activation doesn’t consume endogenous substances. deliver H2S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well[1].

体外研究
(In Vitro)

PRO-F (20 μM; 0-500s) can be activated by light activation (365 nm) time-dependently, λex=530 nm, λem=676 nm[1].
PRO-F (20 μM; 5 min, 10 min, 15 min) produces red fluorescent signal in NDF and HaCaT cells[1].
PRO-F (20 μM; 0-500 s) 可通过时间依赖性光激活 (365 nm) 激活,λex=530 nm,λem=676 nm[1]
PRO-F (20 μM;5 分钟、10 分钟、15 分钟) 在 NDF 和 HaCaT 细胞中产生红色荧光信号[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

591.68

Formula

C34H29N3O5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

PRO-F 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PRO-F
目录号:
HY-149837
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