2. Others Neuronal Signaling GPCR/G Protein Immunology/Inflammation
  3. Adrenergic Receptor mAChR Histamine Receptor Isotope-Labeled Compounds
  4. Promethazine-d4

Promethazine-d4  (Synonyms: (±)-Promethazine-d4; N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine-d4)

目录号: HY-B1296S1
产品使用指南 技术支持

Promethazine-d4 是氘代标记的 Promethazine (HY-B0781)。Promethazine 是具有口服活性的 H1 受体和 mAChR 拮抗剂，具有抗组胺 (H1)、镇静、止吐、抗胆碱能和抗晕动病特性。

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Promethazine-d<sub>4</sub> Chemical Structure

Promethazine-d4 Chemical Structure

CAS No. : 1173147-64-2

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规格 是否有货
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Other Forms of Promethazine-d4:

Promethazine-d4 相关抗体

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查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

查看 mAChR 亚型特异性产品:

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Promethazine-d4 is a deuterated-labeled promethazine (HY-B0781). Promethazine is an orally active H1 receptor and mAChR antagonist with antihistamine (H1), sedative, antiemetic, anticholinergic, and anti-motion sickness properties[1][2][3][4][5][6][7].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Promethazine-d4 相关抗体:
分子量

288.44

Formula

C17H16D4N2S
CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Promethazine-d4 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Promethazine-d41173147-64-2(±)-Promethazine-d4 N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine-d4Adrenergic ReceptormAChRHistamine ReceptorIsotope-Labeled CompoundsBeta ReceptorMuscarinic acetylcholine receptorHistamine Receptor AntagonistantihistamineSW480HCT116HT29Caco2Inhibitorinhibitorinhibit

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