1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Prostaglandin F2α dimethyl amine

Prostaglandin F2α dimethyl amine 

目录号: HY-114761
产品使用指南

Prostaglandin F2α dimethyl amine 是 PGF2α (HY-12956) 衍生物。Prostaglandin F2α dimethyl amine 是前列腺素 F 受体 (FP) 的拮抗剂。Prostaglandin F2α dimethyl amine 可阻断食欲素和 Arachidonic acid (HY-109590) 诱导的心血管反应。

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Prostaglandin F2α dimethyl amine Chemical Structure

Prostaglandin F2α dimethyl amine Chemical Structure

CAS No. : 67508-09-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Prostaglandin F2α dimethyl amine is a Prostaglandin F2α (HY-12956) derivative. Prostaglandin F2α dimethyl amine is an antagonist for Prostaglandin F receptor (FP)[1]. Prostaglandin F2α dimethyl amine blocks the cardiovascular responses induced by orexin and Arachidonic acid (HY-109590)[2].

IC50 & Target

FP

 

体内研究
(In Vivo)

Prostaglandin F2α dimethyl amine (50 µg,脑室内注射,单剂量) 可预防 Sprague-Dawley 大鼠体内由食欲素和 Arachidonic acid (HY-109590) 引起的升压和心动过速[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Orexin-induced cardiovascular response in Sprague Dawley rats[2]
Dosage: 50 µg
Administration: i.c.v for single dose
Result: Prevented the pressor and tachycardic effects.
分子量

367.57

Formula

C22H41NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Prostaglandin F2α dimethyl amine 相关分类

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Prostaglandin F2α dimethyl amine
目录号:
HY-114761
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