2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Angiopoietins
  5. Angiopoietin-Like 7
  6. ANGPTL7/Angiopoietin-related 7 蛋白, Canine (HEK293, Fc)

ANGPTL7/Angiopoietin-related 7 蛋白, Canine (HEK293, Fc)

目录号: HY-P75508
产品使用指南

ANGPTL7/血管生成素相关蛋白是角膜血管生成的负调节因子，在保持角膜血管通畅和透明度方面发挥重要作用。ANGPTL7 受 SP1 转录调控，通过 RhoA/ROCK 信号通路调节 ANGPTL7 水平介导CLAN 形成。ANGPTL7/Angiopoietin-related 7 蛋白, Canine (HEK293, Fc) 是重组的 ANGPTL7/血管生成素相关 7 蛋白，由 HEK293 表达，带有 C-hFc 标签。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

ANGPTL7/ Angiopoietin-related proteins are negative regulators of corneal angiogenesis and play an important role in maintaining the patency and transparency of corneal blood vessels. ANGPTL7 is regulated by SP1 transcription and regulates ANGPTL7 levels through the RhoA/ROCK signaling pathway mediating CLAN formation. ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, Fc) is the recombinant canine-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-hFc labeled tag.
研究背景

ANGPTL7/血管生成素相关蛋白在细胞外基质的形成和组织中起着至关重要的作用。研究表明，特别是在眼睛中，它作为地塞米松诱导的基质沉积在小梁网中的介质，小梁网是眼房水流出和维持眼压所必需的组织。此外，ANGPTL7 是角膜血管生成的负调节因子，在保持角膜血管通畅和透明度方面发挥重要作用。ANGPTL7 受 SP1 转录调控，通过 RhoA/ROCK 信号通路调节 ANGPTL7 水平介导CLAN 形成。
种属

Canine
表达系统

HEK293
标签

C-hFc
蛋白编号

A0A8C0QI96 (Q27-P344)
基因 ID

608972  [NCBI]
蛋白结构
N-term
ANGPTL7 (Q27-P344)
Accession # A0A8C0QI96
hFc
C-term
同用名
Angiopoietin-like factor; ANGPTL7; AngX; CDT6
分子量

Approximately 57 kDa
纯度

Greater than 85% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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