Animal-Free 4-1BBL/TNFSF9 蛋白, Mouse (His)

4-1BBL/TNFSF9 Protein, a cytokine, binds TNFRSF9, inducing proliferation in activated peripheral blood T-cells. It's implicated in activation-induced cell death (AICD) and contributes to cognate interactions between T-cells and B-cells/macrophages. Functioning as a homotrimer enhances its biological activity. Animal-Free 4-1BBL/TNFSF9 Protein, Mouse (His) is the recombinant mouse-derived animal-Free4-1BBL/TNFSF9 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free 4-1BBL/TNFSF9 Protein, Mouse (His) is 108 a.a., with molecular weight of ~23.91 kDa.

4-1BBL/TNFSF9 蛋白是一种细胞因子，可特异性结合 TNFRSF9，触发激活的外周血 T 细胞的增殖。据信它参与激活诱导的细胞死亡 (AICD)，也可能有助于 T 细胞和 B 细胞/巨噬细胞之间的同源相互作用。该蛋白质作为同源三聚体发挥作用，进一步增强其生物活性。

Measure by its ability to induce IL-2 secretion in mouse T cells in the presence of the anti-CD3 antibody. The ED₅₀ for this effect is <0.05 μg/mL.

Mouse

E. coli

C-His

P41274 (R104-T211)

21950  [NCBI]

MRTEPRPALTITTSPNLGTRENNADQVTPVSHIGCPNTTQQGSPVFAKLLAKNQASLCNTTLNWHSQDGAGSSYLSQGLRYEEDKKELVVDSPGLYYVFLELKLSPTFT

Approximately 23.91 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.