1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. B4GALT3 蛋白, Human (HEK293, His)

B4GALT3 蛋白, Human (HEK293, His)

目录号: HY-P7629
产品使用指南

B4GALT3 蛋白, Human (HEK293, His)在肿瘤发生中发挥重要作用。B4GALT3促进胶质母细胞瘤细胞增殖和侵袭。

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描述

B4GALT3 Protein, Human (HEK293, His) promotes cell proliferation and invasion in glioblastoma. B4GALT3 plays an important role in development tumourigenesis[1].

研究背景

B4GALT3 在胶质母细胞瘤中表达上调,预示预后不良。B4GALT3的上调促进GBM细胞增殖和侵袭,而B4GALT3的下调则减少GBM细胞的增殖和侵袭。B4GALT3 通过 β-连环蛋白和波形蛋白调节细胞增殖和侵袭。B[1]。B4GALT3 是一种负责生成聚-N-乙酰基乳糖胺的酶,并参与肿瘤发生[2]

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

O60512 (R32-S392)

基因 ID
蛋白结构
N-term
B4GALT3 (R32-S392)
Accession # O60512
6*His
C-term
中文名
重组人B4GALT3, His 标签 (HEK293-表达)
同用名
rHuB4GALT3, His; Beta-1,4-galactosyltransferase 3; B4GALT3
氨基酸序列

RSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGPPAPQGLPYCPERSPLLVGPVSVSFSPVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQEMLQRRPPARPGPLSTANHTALRGSHHHHHHH

分子量

Approximately 50.0 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
参考文献

B4GALT3 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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B4GALT3 Protein, Human (HEK293, His)
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