Beta-lactamase CTX-M-1/Bla 蛋白, E.coli (His)

Beta-lactamase CTX-M-1/Bla protein is a broad-spectrum beta-lactamase that greatly contributes to antibiotic resistance by hydrolyzing penicillins and cephalosporins (including third-generation drugs). Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) is the recombinant E. coli-derived Beta-lactamase CTX-M-1/Bla protein, expressed by E. coli , with N-His labeled tag. The total length of Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) is 263 a.a., with molecular weight of ~32.2 kDa.

β-内酰胺酶 CTX-M-1/Bla 蛋白是一种广谱 β-内酰胺酶，通过赋予青霉素以及第一、第二和第三代头孢菌素耐药性，在抗生素耐药性中发挥至关重要的作用。其酶活性有助于这些 β-内酰胺抗生素的水解，使细菌能够逃避这些常用药物的抗菌作用。这种耐药机制对细菌感染的临床治疗提出了重大挑战，强调了理解和解决抗生素耐药性分子基础的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

E.coli

E. coli

N-His

P28585 (29Q-291L)

39692553  [NCBI]

QTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAVAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTNGL

Approximately 32.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in Tris-based buffer, 50% glycerol.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.