1. 重组蛋白
  2. Cytokines and Growth Factors Receptor Proteins
  3. Chemokine & Receptors G-Protein-Coupled Receptors (GPCRs)
  4. CC Chemokine Receptor Chemokine Receptor
  5. CCR8
  6. CCR8 蛋白, Mouse (Cell-Free, His)

CCR8 蛋白, Mouse (Cell-Free, His)

目录号: HY-P702237
产品使用指南

CCR8 蛋白作为 CCL1/SCY1/TCA-3 趋化因子的受体,对于介导细胞反应至关重要。它与 CCL1 的相互作用协调关键的趋化信号,调节免疫细胞在细胞微环境中的迁移和定位。CCR8 蛋白, Mouse (Cell-Free, His) 是重组的 CCR8 蛋白,由 E. coli Cell-free 表达,带有 N-10*His 标签。CCR8 蛋白, Mouse (Cell-Free, His) 全长 353 个氨基酸,分子量为 41.5 kDa。

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描述

The CCR8 protein serves as a receptor for the CCL1/SCY1/TCA-3 chemokine and is critical for mediating cellular responses. Its interaction with CCL1 coordinates key chemotactic signaling that regulates immune cell migration and positioning in the cellular microenvironment. CCR8 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived CCR8 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of CCR8 Protein, Mouse (Cell-Free, His) is 353 a.a., with molecular weight of 41.5 kDa.

研究背景

CCR8 蛋白作为 CCL1/SCY1/TCA-3 趋化因子的受体,表明其在介导细胞对该特定趋化因子配体的反应中发挥着至关重要的作用。CCR8CCL1 之间的相互作用对于协调趋化信号事件至关重要,这些信号事件可调节免疫细胞在细胞微环境中的迁移和定位。作为 CCL1 的受体,CCR8 有助于形成复杂的趋化因子信号传导网络,在免疫系统内的免疫反应和细胞通讯中发挥重要作用。

种属

Mouse

表达系统

E. coli Cell-free

标签

N-10*His

蛋白编号

P56484 (M1-L353)

基因 ID

12776

蛋白结构
N-term
10*His
CCR8 (M1-L353)
Accession # P56484
C-term
同用名
C-C chemokine receptor type 8; CD_antigen: CDw198 Cmkbr8; Ter1; C-C CKR-8; CC-CKR-8; CCR-8
氨基酸序列

MDYTMEPNVTMTDYYPDFFTAPCDAEFLLRGSMLYLAILYCVLFVLGLLGNSLVILVLVGCKKLRSITDIYLLNLAASDLLFVLSIPFQTHNLLDQWVFGTAMCKVVSGLYYIGFFSSMFFITLMSVDRYLAIVHAVYAIKVRTASVGTALSLTVWLAAVTATIPLMVFYQVASEDGMLQCFQFYEEQSLRWKLFTHFEINALGLLLPFAILLFCYVRILQQLRGCLNHNRTRAIKLVLTVVIVSLLFWVPFNVALFLTSLHDLHILDGCATRQRLALAIHVTEVISFTHCCVNPVIYAFIGEKFKKHLMDVFQKSCSHIFLYLGRQMPVGALERQLSSNQRSSHSSTLDDIL

分子量

41.5 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CCR8 Protein, Mouse (Cell-Free, His)
目录号:
HY-P702237
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