1. 重组蛋白
  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. CLL-1
  6. CLEC12A/MICL 蛋白, Mouse (HEK293, His)

CLEC12A/MICL 蛋白, Mouse (HEK293, His)

目录号: HY-P77905
COA 产品使用指南

CLEC12A/MICL 蛋白充当细胞表面受体,促进 MAP 激酶的酪氨酸磷酸化并调节信号级联。它与信号通路中的关键蛋白 PTPN6 和 PTPN11 相互作用。CLEC12A/MICL 蛋白, Mouse (HEK293, His) 是重组的 CLEC12A/MICL 蛋白,由 HEK293 表达,带有 N-His 标签。CLEC12A/MICL 蛋白, Mouse (HEK293, His) 全长 203 个氨基酸,分子量为 30-40 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
20 μg ¥1300 In-stock
50 μg ¥2800 In-stock
100 μg   询价  

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描述

CLEC12A/MICL protein acts as a cell surface receptor, facilitating tyrosine phosphorylation of MAP kinases and modulating signaling cascades. It interacts with PTPN6 and PTPN11, key proteins in signaling pathways. CLEC12A/MICL Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag. The total length of CLEC12A/MICL Protein, Mouse (HEK293, His) is 203 a.a., with molecular weight of 30-40 kDa.

研究背景

CLEC12A/MICL 蛋白是一种细胞表面受体,在调节信号级联和促进靶标 MAP 激酶的酪氨酸磷酸化方面发挥着至关重要的作用。它与 PTPN6 和 PTPN11 这两种参与信号传导途径的重要蛋白质相互作用。

种属

Mouse

表达系统

HEK293

标签

N-His

蛋白编号

Q504P2 (Y65-R267)

基因 ID

232413  [NCBI]

蛋白结构
N-term
His
CLEC12A (Y65-R267)
Accession # Q504P2
C-term
同用名
MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
分子量

30-40 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

CLEC12A/MICL Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CLEC12A/MICL Protein, Mouse (HEK293, His)
目录号:
HY-P77905
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