1. 重组蛋白
  2. Enzymes & Regulators
  3. Isomerases (EC 5)
  4. CRELD1 蛋白, Mouse (HEK293, Fc)

CRELD1 蛋白, Mouse (HEK293, Fc)

目录号: HY-P76286
产品使用指南

CRELD1 蛋白是蛋白质二硫键异构酶家族的成员,积极参与有助于重要细胞过程的二硫键重排。特别值得注意的是 CRELD1 在促进乙酰胆碱受体 (AChR) 定位到质膜方面的作用。CRELD1 蛋白, Mouse (HEK293, Fc) 是重组的 CRELD1 蛋白,由 HEK293 表达,带有 C-hFc 标签。CRELD1 蛋白, Mouse (HEK293, Fc) 全长 362 个氨基酸,分子量约为 ~63 KDa。

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描述

The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRELD1 Protein, Mouse (HEK293, Fc) is 362 a.a., with molecular weight of ~63 KDa.

研究背景

CRELD1 蛋白被鉴定为蛋白质二硫键异构酶家族的成员,在细胞过程中发挥着重要作用。这种蛋白质与该家族的其他成员类似,参与二硫键重排。值得注意的是,CRELD1 被发现可以促进乙酰胆碱受体 (AChR) 定位到质膜。这一功能强调了 CRELD1 在关键细胞成分(尤其是乙酰胆碱受体)的组织和定位中的重要性,强调了它对细胞通讯和信号传导过程的潜在影响。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q91XD7 (M1-E362)

基因 ID

171508  [NCBI]

蛋白结构
N-term
CRELD1 (M1-E362)
Accession # Q91XD7
hFc
C-term
同用名
Protein disulfide isomerase CRELD1; Cysteine-rich with EGF-like domain protein 1; CIRRIN
分子量

Approximately 63 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CRELD1 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CRELD1 Protein, Mouse (HEK293, Fc)
目录号:
HY-P76286
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