CTACK/CCL27 蛋白, Mouse

CTACK/CCL27 protein plays a crucial role in chemokine activity and cell chemotaxis. It regulates T cell chemotaxis and actin cytoskeletal reorganization, suggesting its involvement in immune responses and cell motility. CTACK/CCL27 Protein, Mouse is the recombinant mouse-derived CTACK/CCL27 protein, expressed by E. coli , with tag free. The total length of CTACK/CCL27 Protein, Mouse is 95 a.a., with molecular weight of ~11 kDa.

CTACK/CCL27 蛋白通过启用趋化因子活性并参与细胞趋化性发挥着至关重要的作用。它在 T 细胞趋化性正向调节和肌动蛋白细胞骨架重组正向调节的上游发挥作用，表明它参与免疫反应和细胞运动。该蛋白质位于细胞外区域和细胞核，突出了其在细胞过程中的多功能性。CTACK/CCL27 在各种组织（包括泌尿生殖系统、髋部、肝脏、感觉器官和骨骼）中具有广泛的表达模式，对不同的生理环境表现出广泛的影响。与人类 CCL27 的直系同源关系强调了这种趋化因子蛋白在跨物种中的进化保守性和功能相关性。

Measured by its ability to chemoattract HUT78 cells. The ED₅₀ for this effect is 0.0145 μg/mL, corresponding to a specific activity is 6.897×10⁴ U/mg.

Mouse

E. coli

Tag Free

NP_035466 (L26-N120)

20301  [NCBI]

LPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSNPQQQN

Approximately 11 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 4mM HCL, pH 0.8, 5% trehalose, 5% mannitol and 0.01% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.