2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. CXC Chemokines
  6. IP-10/CXCL10
  7. CXCL10 蛋白, Cynomolgus (His)

CXCL10 蛋白, Cynomolgus (His)

目录号: HY-P700980
产品使用指南

CXCL10 蛋白充当单核细胞和 T 淋巴细胞的趋化因子，在它们响应炎症信号的迁移中发挥着至关重要的作用。通过与 CXCR3 结合，CXCL10 选择性地吸引单核细胞和 T 淋巴细胞，使其成为免疫反应的关键参与者，有助于在各种生理和病理情况下招募和激活这些免疫细胞。CXCL10 蛋白, Cynomolgus (His) 是重组的 CXCL10 蛋白，由 E. coli 表达，带有 N-His 标签。CXCL10 蛋白, Cynomolgus (His) 全长 65 个氨基酸，分子量为 12-14 kDa。

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描述

CXCL10 protein acts as a chemotactic factor for monocytes and T-lymphocytes, playing a crucial role in their migration in response to inflammatory signals. Through binding to CXCR3, CXCL10 selectively attracts monocytes and T-lymphocytes, positioning it as a key player in immune responses, contributing to the recruitment and activation of these immune cells in various physiological and pathological contexts. CXCL10 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived CXCL10 protein, expressed by E. coli , with N-His labeled tag. The total length of CXCL10 Protein, Cynomolgus (His) is 65 a.a., with molecular weight of 12-14 kDa.
研究背景

CXCL10 蛋白是单核细胞和 T 淋巴细胞的趋化因子，在协调它们响应炎症信号的迁移中发挥着至关重要的作用。通过与 CXCR3 的结合，CXCL10 建立了一种分子相互作用，促进其化学吸引功能。这种对单核细胞和 T 淋巴细胞的选择性趋化性使 CXCL10 成为免疫反应中的关键参与者，有助于在各种生理和病理环境中招募和激活这些免疫细胞。
种属

Cynomolgus
表达系统

E. coli
标签

N-His
蛋白编号

XP_005555067.1 (T27-K91)
基因 ID

102134351  [NCBI]
蛋白结构
N-term
His
CXCL10 (T27-K91)
Accession # XP_005555067.1
C-term
同用名
C-X-C motif chemokine 10; IP-10; CXCL10(1-73); CXCL10; INP10; SCYB10; C7; crg-2; gIP-10; IFI10;
分子量

12-14 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CXCL10 Protein, Cynomolgus (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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