Dermatopontin/DPT 蛋白, Mouse (HEK293, Fc)

The dermapontin (DPT) protein mediates adhesion by binding to integrins on the cell surface and serves as a communication link between dermal fibroblasts and the extracellular matrix. It enhances TGFB1 activity, inhibits cell proliferation, accelerates collagen fiber formation, and stabilizes its resistance to low-temperature dissociation. Dermatopontin/DPT Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Dermatopontin/DPT protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Dermatopontin/DPT Protein, Mouse (HEK293, Fc) is 183 a.a., with molecular weight of ~55 kDa.

皮桥蛋白 (DPT) 蛋白通过与细胞表面整合素结合而充当粘附介质，并充当真皮成纤维细胞表面和细胞外基质之间的潜在通讯纽带。此外，DPT还能增强TGFB1的活性，抑制细胞增殖，并在加速胶原纤维形成的同时稳定胶原纤维以防止低温解离。它与 TGFB1、DCN 和胶原蛋白的相互作用强调了它参与细胞粘附和细胞外基质动力学的调节。

Mouse

HEK293

C-hFc

Q9QZZ6 (Q19-V201)

56429  [NCBI]

QYGGYGYPYQQYQDYGDDGWVNLNRQGFSYQCPHGQVVVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQKCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPSHYGEDMDMISYDYDFYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFENV

Approximately 55 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.