FAAH2 蛋白, Human (Cell-Free, His)

FAAH2 proteins play a central role in cellular processes by catalyzing the hydrolysis of endogenous amidated lipids, including the sleep-inducing lipid oleamide ((9Z)-octadecylamide) and the endocannabinoid anandamide (N-(5Z) , 8Z, 11Z, 14Z-eicosate tetraenoyl)))-ethanolamine) and other fatty amides. FAAH2 Protein, Human (Cell-Free, His) is the recombinant human-derived FAAH2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of FAAH2 Protein, Human (Cell-Free, His) is 532 a.a., with molecular weight of 59.8 kDa.

脂肪酸酰胺水解酶 2 (FAAH2) 是一种催化内源性酰胺化脂质水解的酶，包括诱导睡眠的脂质油酰胺 ((9Z)-十八烯酰胺) 和内源性大麻素大麻酰胺 (N-(5Z,8Z,11Z,14Z-)二十碳四烯酰)-乙醇胺)。FAAH2 通过将这些生物活性分子转化为相应的脂肪酸，在调节这些生物活性分子的信号传导功能方面发挥着至关重要的作用。该酶表现出对单不饱和底物（如花生四烯酸乙醇胺）的偏好，而不是多不饱和底物。这种对酰胺化脂质的水解活性表明 FAAH2 参与各种生理过程的控制和调节，包括与睡眠调节和内源性大麻素信号传导相关的生理过程。它必须简洁地描述 FAAH2 的底物特异性及其在调节内源酰胺化脂质信号传导功能中的作用。

Human

E. coli Cell-free

N-10*His

Q6GMR7 (M1-F532)

158584

MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF

59.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.