FASN 蛋白, Human (Sf9, His)

FASN (fatty acid synthase) is a multifunctional enzyme that is key to the de novo biosynthesis of long-chain saturated fatty acids from acetyl-CoA and malonyl-CoA using NADPH. This multifunctional protein contains seven catalytic activities and has an acyl carrier protein (ACP) domain with a binding site for the prosthetic group 4'-phosphopantetheine. FASN Protein, Human (Sf9, His) is the recombinant human-derived FASN protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of FASN Protein, Human (Sf9, His) is 416 a.a., .

脂肪酸合酶 (FASN) 是一种多功能酶，对于长链饱和脂肪酸的从头生物合成至关重要，在 NADPH 存在下利用乙酰辅酶 A 和丙二酰辅酶 A。这种多功能蛋白质具有七种催化活性和酰基载体蛋白 (ACP) 结构域的辅基 4'-磷酸泛硫氨酸的结合位点。值得注意的是，FASN 在 SARS 冠状病毒-2 (SARS-CoV-2)（导致 COVID-19 的病毒）的复制中发挥着关键作用，因为其酶活性是病毒复制过程所必需的。

Human

Sf9 insect cells

N-8*His

P49327 (Q1109-G1524)

2194

47.2 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 200 mM NaCl, 10% glycerol, pH 7.5, 1 mM DTT.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.