1. 重组蛋白
  2. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  3. FGF Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  4. FGFR
  5. FGFR-5/FGFRL1
  6. FGFRL1 蛋白, Human (HEK293, His)

FGFRL1 蛋白, Human (HEK293, His)

目录号: HY-P72643
产品使用指南

FGFRL1 蛋白对细胞增殖产生负面影响,揭示了其在细胞生长过程中作为潜在调节剂的作用。此外,它还与 FGF2 相互作用,对这种成纤维细胞生长因子表现出显着但较低的亲和力。FGFRL1 蛋白, Human (HEK293, His) 是重组的 FGFRL1 蛋白,由 HEK293 表达,带有 C-6*His 标签。FGFRL1 蛋白, Human (HEK293, His) 全长 354 个氨基酸,分子量约为 ~65 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The FGFRL1 protein negatively affects cell proliferation, revealing its role as a potential regulator during cell growth. In addition, it interacts with FGF2, showing significant but low affinity for this fibroblast growth factor. FGFRL1 Protein, Human (HEK293, His) is the recombinant human-derived FGFRL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGFRL1 Protein, Human (HEK293, His) is 354 a.a., with molecular weight of ~65 kDa.

研究背景

FGFRL1(成纤维细胞生长因子受体样 1)是一种以其对细胞增殖的负调节作用而闻名的蛋白质。与典型的成纤维细胞生长因子受体不同,FGFRL1 与成纤维细胞生长因子家族成员 FGF2 表现出低亲和力相互作用。这种独特的结合特征表明 FGFRL1 在调节细胞对 FGF 信号传导的反应中具有独特的作用,可能影响细胞生长和分化。对细胞增殖的负面影响表明 FGFRL1 作为细胞过程中的调节成分,而它与 FGF2 的相互作用凸显了它在微调 FGF 介导的信号通路中的潜在参与。所提供的信息基于参考通道,正在进行的研究可能会进一步阐明FGFRL1在细胞调节中的具体机制和下游效应。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8N441 (A25-P378)

基因 ID
蛋白结构
N-term
FGFRL1 (A25-P378)
Accession # Q8N441
6*His
C-term
同用名
Fibroblast growth factor receptor-like 1; FGFR-5; FGFRL1; FGFR5; FHFR
氨基酸序列

ARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWP

分子量

Approximately 65 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
FGFRL1 Protein, Human (HEK293, His)
目录号:
HY-P72643
需求量: