2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CAR-T related Proteins CD Antigens Fluorescent-labeled Recombinant Proteins
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules NK Cell CD Proteins Macrophage CD Proteins
  5. TNF Superfamily Ligands CD70
  6. CD27 Ligand
  7. FITC-Labeled CD70 Trimer 蛋白, Human (HEK293, His-Flag)

FITC-Labeled CD70 Trimer 蛋白, Human (HEK293, His-Flag)

目录号: HY-P701287
产品使用指南

作为CD27的配体，CD70蛋白是T细胞免疫协调中不可或缺的一部分，在抗病毒反应中尤其重要。CD70-CD27 通路成为 T 细胞介导的免疫反应产生和维持的关键参与者。FITC-Labeled CD70 Trimer 蛋白, Human (HEK293, His-Flag) 是重组的 FITC 标记的 CD70 三聚体蛋白，由 HEK293 表达，带有 His 标签。FITC-Labeled CD70 Trimer 蛋白, Human (HEK293, His-Flag) 全长 142 个氨基酸，糖基化后的分子量为 50-55 kDa。

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描述

As a ligand of CD27, CD70 protein is an indispensable part of T cell immune coordination and is of particular importance in antiviral responses. The CD70-CD27 pathway emerged as a key player that contributes to the generation and maintenance of T cell-mediated immune responses. FITC-Labeled CD70 Trimer Protein, Human (HEK293, His-Flag) is the recombinant human-derived FITC-Labeled CD70 Trimer protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled CD70 Trimer Protein, Human (HEK293, His-Flag) is 142 a.a., with molecular weight (glycosylation form) of 50-55 kDa.
研究背景

CD70 是一种作为 CD27 配体的细胞因子，是 CD70-CD27 途径的组成部分，该途径在 T 细胞免疫的发展和维持中发挥着至关重要的作用，特别是在抗病毒反应中。与 CD27 结合后，CD70 会诱导共刺激 T 细胞的增殖，并放大溶细胞 T 细胞的产生，从而有助于有效的免疫反应。在结构上，CD70 形成同源三聚体，反映了其分子组织。CD70-CD27 相互作用强调了其在协调 T 细胞介导的免疫反应中的重要性，为免疫功能的调节提供了宝贵的见解。
种属

Human
表达系统

HEK293
标签

His
蛋白编号

P32970 (S52-P193)
基因 ID

970
同用名
CD70; CD27LG; TNFSF7; TNFSF7G; CD27L
分子量

50-55 kDa under non-reducing (NR) condition due to glycosylation.
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

FITC-Labeled CD70 Trimer Protein, Human (HEK293, His-Flag) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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