1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Neurotrophic Factors
  4. GMF-beta 蛋白, Mouse

GMF-beta 蛋白, Mouse

目录号: HY-P72801
COA 产品使用指南

GMF-β蛋白是一种多方面的调节因子,可协调脑细胞分化、刺激神经再生并抑制肿瘤细胞增殖。佛波酯引发的磷酸化对其活性至关重要,表明响应外部信号的动态调节机制。GMF-beta 蛋白, Mouse 是重组的 GMF-β 蛋白,由 E. coli 表达,不带标签。GMF-beta 蛋白, Mouse 全长 141 个氨基酸,分子量约为 ~19.7 kDa。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
Free Sample   Apply now  
2 μg ¥350 In-stock
10 μg ¥1000 In-stock
50 μg ¥2820 In-stock
100 μg ¥4800 In-stock
500 μg ¥13450 In-stock
1 mg ¥22850 In-stock
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

GMF-β protein is a multifaceted regulatory factor that coordinates brain cell differentiation, stimulates neuroregeneration, and inhibits tumor cell proliferation. Phosphorylation initiated by phorbol esters is critical for its activity, suggesting a dynamic regulatory mechanism in response to external signals. GMF-beta Protein, Mouse is the recombinant mouse-derived GMF-beta protein, expressed by E. coli , with tag free. The total length of GMF-beta Protein, Mouse is 141 a.a., with molecular weight of ~19.7 kDa.

研究背景

GMF-β 蛋白作为多方面的调节剂出现,协调脑细胞的分化,刺激神经再生,同时抑制肿瘤细胞的增殖。这种多功能蛋白质会经历磷酸化,这是一种对其活性至关重要的修饰,尤其是由佛波酯触发。GMF-β 的磷酸化状态表明了一种响应外部信号的动态调节机制,可能在细胞信号级联中发挥关键作用。凭借其影响神经发育和阻碍肿瘤细胞增殖的双重能力,GMF-β 在细胞命运和功能的复杂调节中发挥着关键作用,有望进一步探索理解和操纵这些基本生物过程。

生物活性

Data is not available.

种属

Mouse

表达系统

E. coli

标签

Tag Free

蛋白编号

Q9CQI3 (S2-H142)

基因 ID

63985  [NCBI]

蛋白结构
N-term
GMF-beta (S2-H142)
Accession # Q9CQI3
C-term
同用名
Glia maturation factor beta; GMF-beta; Gmfb
氨基酸序列

SESLVVCDVAEDLVEKLRKFRFRKETHNAAIIMKIDKDERLVVLDEELEGVSPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH

分子量

Approximately 19.7 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

内毒素含量

<1 EU/μg; determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

GMF-beta Protein, Mouse 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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