HADHB 蛋白, Human (GST)

HADHB protein is an important component of mitochondrial trifunctional enzymes and directs three decisive reactions in the mitochondrial β-oxidation pathway. This pathway is critical for generating energy across tissues, breaking down long-chain fatty acids into acetyl-CoA. HADHB Protein, Human (GST) is the recombinant human-derived HADHB protein, expressed by E. coli , with N-GST labeled tag. The total length of HADHB Protein, Human (GST) is 249 a.a., with molecular weight of ~53.8 kDa.

HADHB 蛋白是线粒体三功能酶的组成部分，协调线粒体 β-氧化途径中的最后三个反应。这一关键途径对于各种组织的能量产生至关重要，通过一系列四个连续反应将脂肪酸分解为乙酰辅酶A。这种三功能酶专为长链脂肪酸定制，作为由两个不同亚基组成的异四聚体复合物发挥作用。HADHA 携带 2,3-烯酰基-CoA 水合酶和 3-羟酰基-CoA 脱氢酶活性，与 HADHB 合作，HADHB 是这里的焦点，后者具有 3-酮酰基-CoA 硫解酶活性。这种复杂的合作强调了 HADHB 在驱动线粒体 β 氧化的最后步骤中的关键作用，有助于细胞代谢中的能量稳态。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-GST

P55084 (35A-283P)

3032  [NCBI]

APAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRP

Approximately 53.8 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in Tris-based buffer, 50% glycerol.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.