2. 重组蛋白
  3. Viral Proteins
  4. Hemagglutinin glycoprotein 蛋白, Measles virus (Cell-Free, His)

Hemagglutinin glycoprotein 蛋白, Measles virus (Cell-Free, His)

目录号: HY-P702315
产品使用指南

血凝素糖蛋白通过将病毒与细胞受体结合来启动感染，诱导 F 蛋白触发的融合构象变化。它可能使用 CD46 和/或 SLAMF1 受体进入，导致 CD46 下调，增强补体裂解的敏感性。H 蛋白还与 NECTIN4 相互作用，促进呼吸道上皮中的病毒感染。Hemagglutinin glycoprotein 蛋白, Measles virus (Cell-Free, His) 是重组的 血凝素糖蛋白 蛋白，由 E. coli Cell-free 表达，带有 N-10*His 标签。Hemagglutinin glycoprotein 蛋白, Measles virus (Cell-Free, His) 全长 617 个氨基酸，分子量为 75.4 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The Hemagglutinin glycoprotein initiates infection by binding the virus to cell receptors, inducing a conformational change for fusion triggered by the F protein. It may use CD46 and/or SLAMF1 receptors for entry, leading to down-regulation of CD46, enhancing susceptibility to complement lysis. H protein also interacts with NECTIN4, facilitating viral infection in the respiratory epithelium. Hemagglutinin glycoprotein Protein, Measles virus (Cell-Free, His) is the recombinant Virus-derived Hemagglutinin glycoprotein protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Hemagglutinin glycoprotein Protein, Measles virus (Cell-Free, His) is 617 a.a., with molecular weight of 75.4 kDa.
研究背景

血凝素糖蛋白通过将病毒附着在细胞受体上，在感染的启动中发挥着至关重要的作用。与受体结合后，H 蛋白会诱导构象变化，从而促进 F 蛋白触发病毒颗粒与细胞膜之间的融合。该病毒可能利用人类 CD46 和/或 SLAMF1 作为细胞进入的受体。H 和 MCP/CD46 之间的强烈相互作用导致后者在受感染细胞表面的下调，从而增强了它们对 c3b 介导的补体裂解的敏感性。此外，H 蛋白与人 NECTIN4 相互作用，导致呼吸道上皮细胞发生病毒感染。
种属

Virus
表达系统

E. coli Cell-free
标签

N-10*His
蛋白编号

P35971 (M1-R617)
基因 ID

/
蛋白结构
N-term
10*His
MV-H (M1-R617)
Accession # P35971
C-term
同用名
Hemagglutinin glycoprotein
氨基酸序列

MSPQRDRINAFYKDNPHPKGSRIVINREHLMIDRPYVLLAVLFVMFLSLIGLLAIAGIRLHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLGRGYNVSSIVTMTSQGMYGGTYLVEKPNLSSKRSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYLEQPVSNDLSNCMVALGELKLAALCHREDSITIPYQGSGKGVSFQLVKLGVWKSPTDMQSWVTLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACKGKIQALCENPEWAPLKDNRIPSYGVLSVDLSLTVELKIKIASGFGPLITHGSGMDLYKSNHNNVYWLTIPPMKNLALGVINTLEWIPRFKVSPYLFNVPIKEAGEDCHAPTYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPSRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMVGMGVSCTVTREDGTNRR

分子量

75.4 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Hemagglutinin glycoprotein Protein, Measles virus (Cell-Free, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Hemagglutinin glycoprotein Protein, Measles virus (Cell-Free, His)
目录号：
HY-P702315
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z