HSPB8 蛋白, Human (His)

The HSPB8 protein exhibits temperature-dependent chaperone activity and functions as a monomer in its molecular form. It interacts with other cellular proteins to form complexes critical for cellular homeostasis. HSPB8 Protein, Human (His) is the recombinant human-derived HSPB8 protein, expressed by E. coli , with C-6*His labeled tag. The total length of HSPB8 Protein, Human (His) is 196 a.a., with molecular weight of ~23.0 kDa.

HSPB8（热休克蛋白家族 B [小] 成员 8）表现出温度依赖性伴侣活性，作为单体发挥作用。它与 HSPB1 相互作用，表明在细胞蛋白质折叠和质量控制机制中具有潜在的协同作用。此外，HSPB8 与 DNAJB6 相互作用，表明它参与更广泛的伴侣蛋白网络。与 BAG3 的相互作用进一步强调了其在蛋白质稳态中的作用，因为 BAG3 与蛋白质降解过程的调节有关。这些相互作用共同凸显了 HSPB8 在细胞应激反应和蛋白质质量控制中的多功能性，使其成为维持蛋白质稳态的关键角色。

Human

E. coli

C-6*His

Q9UJY1 (M1-T196)

26353  [NCBI]

MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT

Approximately 23.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 mM EDTA, pH 7.4.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.