2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-33
  6. IL-33 蛋白, Cynomolgus (HEK293, His)

IL-33 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P77966
产品使用指南

IL-33 蛋白是 IL-1 家族的一部分，是一种在免疫反应和炎症中至关重要的不同细胞因子。IL-33 通过其受体 ST2 发挥作用，促进 Th2 细胞、肥大细胞和嗜酸性粒细胞等免疫细胞的激活和募集到炎症部位。IL-33 由上皮细胞和内皮细胞产生，可诱导促炎细胞因子和趋化因子。IL-33 与哮喘、过敏性疾病和自身免疫性疾病有关，成为免疫反应调节的治疗靶点。IL-33 蛋白, Cynomolgus (HEK293, His) 是重组的 IL-33 蛋白，由 HEK293 表达，带有 N-His 标签。IL-33 蛋白, Cynomolgus (HEK293, His) 全长 162 个氨基酸，分子量为 25-30 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

IL-33 Protein, part of the IL-1 family, is a divergent cytokine pivotal in immune responses and inflammation. Operating through its receptor ST2, IL-33 promotes activation and recruitment of immune cells like Th2 cells, mast cells, and eosinophils to inflammation sites. Produced by epithelial and endothelial cells, IL-33 induces pro-inflammatory cytokines and chemokines. Implicated in asthma, allergic diseases, and autoimmune disorders, IL-33 emerges as a therapeutic target for immune response modulation. IL-33 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-33 protein, expressed by HEK293, with N-His labeled tag. The total length of IL-33 Protein, Cynomolgus (HEK293, His) is 162 a.a., with molecular weight of 25-30 kDa.
研究背景

IL-33 蛋白属于 IL-1 家族，因其与其他家族成员的高度差异而闻名。它作为一种重要的细胞因子参与各种免疫反应和炎症过程。IL-33 在促进免疫细胞（例如辅助性 T 2 (Th2) 细胞、肥大细胞和嗜酸性粒细胞）激活和募集到炎症部位方面发挥着至关重要的作用。它主要由上皮细胞和内皮细胞产生，并通过其受体 ST2 发挥作用，诱导其他促炎细胞因子和趋化因子的产生。IL-33 与多种疾病有关，包括哮喘、过敏性疾病和自身免疫性疾病，凸显了其作为调节免疫反应的治疗靶点的重要性。
种属

Cynomolgus
表达系统

HEK293
标签

N-His
蛋白编号

A0A2K5W3I1 (H109-I270)
基因 ID

102140695  [NCBI]
蛋白结构
N-term
His
IL-33 (H109-I270)
Accession # A0A2K5W3I1
C-term
同用名
C9orf26 Z; DVS27; IL1F11; NF-HEV; NFEHEV; IL33; DV27; C9ORF26; RP11-575C20.2
分子量

25-30 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

IL-33 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
IL-33 Protein, Cynomolgus (HEK293, His)
目录号：
HY-P77966
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z