1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. IL1RAPL1 蛋白, Human (HEK293, His)

IL1RAPL1 蛋白, Human (HEK293, His)

目录号: HY-P70923
产品使用指南

IL1RAPL1 蛋白是一种多方面的调节因子,可能抑制 N 型钙通道,影响分泌和突触前分化。它可能激活 MAP 激酶 JNK,表明参与细胞内信号传导。IL1RAPL1 蛋白, Human (HEK293, His) 是重组的 IL1RAPL1 蛋白,由 HEK293 表达,带有 C-6*His 标签。IL1RAPL1 蛋白, Human (HEK293, His) 全长 339 个氨基酸,分子量为 50-70 kDa。

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描述

IL1RAPL1 protein is a multifaceted regulator that may inhibit N-type calcium channels, affecting secretion and presynaptic differentiation. It may activate MAP kinase JNK, suggesting involvement in intracellular signaling. IL1RAPL1 Protein, Human (HEK293, His) is the recombinant human-derived IL1RAPL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IL1RAPL1 Protein, Human (HEK293, His) is 339 a.a., with molecular weight of 50-70 kDa.

研究背景

IL1RAPL1 蛋白作为多方面的调节剂出现,通过抑制 N 型电压门控钙通道的活性,可能影响分泌和突触前分化。此外,它还可能激活 MAP 激酶 JNK,表明它可能参与细胞内信号传导途径。IL1RAPL1 与神经突生长有关,强调了其在神经元发育中的作用。值得注意的是,在树突棘形成过程中,IL1RAPL1 表现出双向能力,通过跨突触结合 PTPRD 诱导神经元突触前和突触后分化。IL1RAPL1 的多种功能作用强调了它在协调与突触功能、神经元发育和细胞内信号通路相关的复杂细胞过程中的重要性,值得进一步探索其精确的分子机制和在神经元生物学中更广泛的影响。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q9NZN1 (L19-T357)

基因 ID
蛋白结构
N-term
IL1RAPL1 (L19-T357)
Accession # Q9NZN1
6*His
C-term
同用名
Interleukin-1 Receptor Accessory Protein-Like 1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; Oligophrenin-4; Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2; TIGIRR-2; X-Linked Interleukin-1 Receptor Accessory Protein-Like 1; IL1RAPL1; OPHN4
氨基酸序列

LKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPMESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYT

分子量

50-70 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IL1RAPL1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IL1RAPL1 Protein, Human (HEK293, His)
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