LALBA 蛋白, Human (HEK293, His)

LALBA proteins are regulatory subunits of lactose synthase and play a key role in altering the substrate specificity of mammary galactosyltransferase. This modification allows galactosyltransferase to utilize glucose, promoting the synthesis of lactose - the main milk carbohydrate. LALBA Protein, Human (HEK293, His) is the recombinant human-derived LALBA protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LALBA Protein, Human (HEK293, His) is 123 a.a., with molecular weight of 14 kDa.

LALBA 蛋白作为乳糖合成酶的调节亚基，在改变乳腺内半乳糖基转移酶的底物特异性方面发挥着关键作用。这种修饰使半乳糖基转移酶能够利用葡萄糖作为有效的受体底物，促进乳糖（牛奶的主要碳水化合物成分）的合成。除了参与乳糖合成之外，在各种组织中，半乳糖基转移酶还将半乳糖转移到糖蛋白中寡糖链的 N-乙酰氨基葡萄糖上。作为乳糖合成酶 (LS) 的一部分，LALBA 与催化成分 β1,4-半乳糖基转移酶 (β4Gal-T1) 协作，形成异二聚体复合物，协调复杂的乳糖生产过程，从而构成牛奶的基本成分。

Human

HEK293

C-6*His

P00709 (K20-L142)

3906  [NCBI]

KQFTKCELSQLLKDIDGYGGIALPELICTMFHTSGYDTQAIVENNESTEYGLFQISNKLWCKSSQVPQSRNICDISCDKFLDDDITDDIMCAKKILDIKGIDYWLAHKALCTEKLEQWLCEKL

14 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.